Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.64 |
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | GNG2 | P59768 | 2/20 | 0.52 |
| ▸ | GNB1 | P62873 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30682591 | 1.00 | NR4A2 (0.64) | NR4A2NCF1GNG2GNB1MPO | |
| SCHEMBL439684 | 0.85 | NCF1 (0.59) | NR4A2NCF1GNG2GNB1MPO | |
| SCHEMBL14960133 | 0.81 | POLB (0.61) | NR4A2MPOMEN1KMT2AALDH1A1 | |
| SCHEMBL858917 | 0.78 | MAPT (0.56) | NR4A2MPOMEN1KMT2AACHE | |
| SCHEMBL442241 | 0.78 | NR4A2 (0.64) | NR4A2NCF1GNG2GNB1MPO | |
| SCHEMBL438119 | 0.78 | NR4A2 (1.00) | NR4A2NCF1GNG2GNB1MPO | |
| SCHEMBL3267043 | 0.78 | MPO (0.46) | NR4A2MPOALDH1A1HSD17B10ACHE | |
| SCHEMBL10175203 | 0.76 | ALDH1A1 (0.43) | NR4A2MPOALDH1A1HSD17B10ACHE | |
| SCHEMBL26390863 | 0.75 | KDM4E (0.45) | NR4A2MPOKMT2AALDH1A1HSD17B10 | |
| SCHEMBL2608429 | 0.75 | MPO (0.41) | NR4A2MPOACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |