Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.62 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GNG2 | P59768 | 2/20 | 0.45 |
| ▸ | GNB1 | P62873 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438119 | 0.77 | NR4A2 (1.00) | NR4A2NCF1ALDH1A1CASP1CASP7 | |
| SCHEMBL440491 | 0.77 | NR4A2 (0.74) | NR4A2NCF1ALDH1A1CASP1CASP7 | |
| SCHEMBL14498166 | 0.73 | SLC2A1 (0.55) | NR4A2NCF1ALDH1A1CASP1CASP7 | |
| SCHEMBL438576 | 0.73 | MCHR1 (0.49) | — | |
| SCHEMBL3235863 | 0.72 | NCF1 (0.63) | NR4A2NCF1ALDH1A1CASP1CASP7 | |
| SCHEMBL438604 | 0.72 | NCF1 (0.63) | NR4A2NCF1ALDH1A1CASP1CASP7 | |
| Hydrochloric Acid SCHEMBL30579056 | 0.71 | NCF1 (0.61) | NR4A2NCF1ALDH1A1CASP1CASP7 | |
| SCHEMBL1120035 | 0.69 | NCF1 (1.00) | NR4A2NCF1ALDH1A1CASP1CASP7 | |
| SCHEMBL29557788 | 0.69 | NCF1 (1.00) | NR4A2NCF1ALDH1A1CASP1CASP7 | |
| SCHEMBL440270 | 0.69 | NR4A2 (0.62) | NR4A2NCF1ALDH1A1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |