Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.64 |
| ▸ | DRD2 | P14416 | 15/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.64 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7203533 | 0.99 | DRD3 (0.63) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4380177 | 0.96 | DRD3 (0.64) | DRD3DRD2KCNH2HRH1HTR1A | |
| Hydrochloric Acid SCHEMBL7204494 | 0.95 | DRD3 (0.63) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4386717 | 0.88 | DRD3 (0.61) | DRD3DRD2KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL7203245 | 0.87 | DRD3 (0.60) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4389064 | 0.86 | DRD3 (0.69) | DRD3DRD2KCNH2HRH1HTR1A | |
| SCHEMBL4386792 | 0.84 | DRD3 (0.63) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4387226 | 0.84 | DRD3 (0.61) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4378938 | 0.84 | DRD3 (0.63) | DRD3DRD2KCNH2HRH1HTR1A | |
| SCHEMBL4389062 | 0.83 | DRD3 (0.63) | DRD3DRD2KCNH2HRH1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144405-B1 | TRIAZOLE COMPOUNDS WITH DOPAMINE-D3-RECEPTOR AFFINITY | ABBOTT GMBH & CO KG (DE) | 2009-11-25 | — | — | EP | disclosed |