Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | NPC1 | O15118 | 7/20 | 0.70 |
| ▸ | PKM | P14618 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592795 | 0.87 | GAA (0.56) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL4395297 | 0.84 | RAB9A (0.78) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL8473023 | 0.83 | MEN1 (0.65) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL9750118 | 0.83 | NPC1 (0.81) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL30565139 | 0.83 | RAB9A (1.00) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL10854689 | 0.82 | RAB9A (0.58) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL3078691 | 0.81 | RAB9A (0.73) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL519066 | 0.81 | RAB9A (0.73) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL8665367 | 0.80 | RAB9A (0.66) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL10383050 | 0.80 | GAA (0.58) | RAB9ANPC1PKMGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 983 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250205258-A1 | DERIVATIVES OF BUFALIN AND THEIR PREPARATION METHODS, AS WELL AS COMPOSITIONS, PREPARATIONS, AND APPLICATIONS | SHANGHAI MEWSGEN BIOTECHNOLOGY CO LTD (CN) | 2025-06-26 | — | — | US | claimed |
| WO-2024131776-A1 | BUFALIN DERIVATIVE AND PREPARATION METHOD THEREFOR, COMPOSITION, PREPARATION, AND APPLICATION | 上海邈基生物科技有限公司 | 2024-06-27 | — | — | WO | claimed |
| WO-2024026372-A2 | HYDROGEN BONDING BOTTLEBRUSH POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-02-01 | — | — | WO | claimed |
| CN-117466906-A | Oridonin derivative, preparation method thereof, pharmaceutical composition and application | 中国人民解放军海军军医大学 | 2024-01-30 | — | — | CN | claimed |
| CN-117265602-A | Trivalent chromium blue electroplating solution and preparation method thereof | 无锡比亚汽车零部件有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-117024503-A | Bufotalin phosphate derivative, and pharmaceutical composition, preparation and application thereof | 上海邈基生物科技有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-111526877-B | Compounds and compositions for IRE1 inhibition | 奥普提卡拉公司 | 2023-08-25 | — | — | CN | claimed |
| CN-115109049-A | Triazine compound containing aryl urea structure and application thereof | 江西科技师范大学 | 2022-09-27 | — | — | CN | claimed |
| EP-3728217-A1 | CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS | Ravenna Pharmaceuticals, Inc. (US) | 2020-10-28 | — | — | EP | claimed |
| CN-109694471-B | Pyridyl urea catalyst and application thereof in ring-opening polymerization | 浙江大学 | 2020-08-14 | — | — | CN | claimed |
| EP-0408524-A1 | (Pyrrolidin-2-on-l-yl) acetamides as enhancers of learning and memory and pharmaceutical compositions comprising same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1991-01-16 | — | — | EP | claimed |
| EP-0200299-B1 | PYRIDINYLIMIDAZOLIDINONE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1990-10-10 | — | — | EP | claimed |
| EP-0364428-A1 | Vulcanizable synthetic rubber compositions cure-activated by substituted ureas | Monsanto Company (US) | 1990-04-18 | — | — | EP | claimed |
| EP-0243450-A4 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1989-09-11 | — | — | EP | claimed |
| US-4818271-A | PLANT GROWTH REGULATORS | FMC CORPORATION (US) | 1989-04-04 | — | — | US | claimed |
| EP-0243450-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1987-11-04 | — | — | EP | claimed |
| CN-86107258-A | Pyridyl carbamide compound and on agricultural, using | — | 1987-05-27 | — | — | CN | claimed |
| WO-1987002665-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC CORPORATION (US) | 1987-05-07 | — | — | WO | claimed |
| EP-0200299-A1 | Pyridinylimidazolidinone compounds | ELI LILLY AND COMPANY (US) | 1986-11-05 | — | — | EP | claimed |
| CN-86100928-A | The herbicidal composition and the production method thereof that contain Pyridinylimidazoles alkane ketone compound | — | 1986-08-20 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250205258-A1 | DERIVATIVES OF BUFALIN AND THEIR PREPARATION METHODS, AS WELL AS COMPOSITIONS, PREPARATIONS, AND APPLICATIONS | KCNN1, KCNN2, KCNJ1 | RAB9A 2168/4885NPC1 398/4885PKM 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.