SCHEMBL8665367

SCHEMBL8665367

NNC(=O)Nc1ccccn1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.66
NPC1 O15118 8/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
ADORA3 P0DMS8 1/20 0.66
PIM1 P11309 1/20 0.66
ADORA2A P29274 1/20 0.66
ADORA2B P29275 1/20 0.66
ADORA1 P30542 1/20 0.66
FLT3 P36888 1/20 0.66
PIM3 Q86V86 1/20 0.66
AURKB Q96GD4 1/20 0.66
PKM P14618 3/20 0.66
LMNA P02545 1/20 0.62
GAA P10253 1/20 0.61
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
TSHR P16473 1/20 0.57
HTT P42858 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750118 0.88 NPC1 (0.81) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL10989725 0.81 GAA (0.55) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL29940946 0.81 RAB9A (0.62) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL11279908 0.81 RAB9A (0.66) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL18469876 0.81 RAB9A (0.66) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL438214 0.80 RAB9A (0.70) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL30565139 0.79 RAB9A (1.00) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL9317689 0.79 RAB9A (1.00) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL13430977 0.79 NPC1 (0.68) RAB9ANPC1SMN1; SMN2ADORA3PIM1
SCHEMBL29128678 0.78 RAB9A (0.66) RAB9ANPC1SMN1; SMN2ADORA3PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646574-B1 Ketonic indane derivatives, their preparation and therapeutic application thereof INNOTHERA LAB SA (FR) 1998-12-09 EP claimed
EP-0646574-A1 Ketonic indane derivatives, their preparation and therapeutic application thereof LABORATOIRE INNOTHERA Société Anonyme (FR) 1995-04-05 EP claimed
CN-122010896-A Bicyclol derivative, pharmaceutical composition thereof, preparation method and application thereof 中国医学科学院药物研究所 2026-05-12 CN disclosed
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 US disclosed
US-12269800-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-02-13 US disclosed
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2024-07-25 US disclosed
US-11999694-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-5098462-A Herbicides SANDOZ LTD. (CH) 1992-03-24 US disclosed
US-4451653-A INSECTICIDCES THE DOW CHEMICAL COMPANY (US) 1984-05-29 US disclosed
US-4433148-A CHEMICAL INTERMEDIATES FOR TRIAZOLYL PHOSPHORUS INSECTICIDWS THE DOW CHEMICAL CO. (US) 1984-02-21 US disclosed
US-4400516-A PYRIDINE OR QUINOLINE SUBSTITUTED PESTICIDES THE DOW CHEMICAL CO. (US) 1983-08-23 US disclosed
US-4357327-A Heterocyclic substituted triazolyl phosphorous compounds and their use as insecticides THE DOW CHEMICAL CO. (US) 1982-11-02 US disclosed
US-4357328-A Heterocyclic substituted triazolyl phosphorous compounds and their use as insecticides THE DOW CHEMICAL CO. (US) 1982-11-02 US disclosed
EP-0010891-B1 HETEROCYCLIC SUBSTITUTED TRIAZOLYL PHOSPHOROUS COMPOUNDS, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHOD FOR CONTROLLING INSECTS THE DOW CHEMICAL COMPANY (US) 1982-09-01 EP disclosed
US-4298602-A MITICIDES THE DOW CHEMICAL COMPANY (US) 1981-11-03 US disclosed
EP-0010891-A1 Heterocyclic substituted triazolyl phosphorous compounds, insecticidal compositions containing them and method for controlling insects THE DOW CHEMICAL COMPANY (US) 1980-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT RAB9A 571/4885NPC1 296/4885SMN1; SMN2 95/4885
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT RAB9A 571/4885NPC1 296/4885SMN1; SMN2 95/4885
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT RAB9A 571/4885NPC1 296/4885SMN1; SMN2 95/4885
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT RAB9A 571/4885NPC1 296/4885SMN1; SMN2 95/4885
US-12269800-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT RAB9A 571/4885NPC1 296/4885SMN1; SMN2 95/4885
US-11999694-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT RAB9A 571/4885NPC1 296/4885SMN1; SMN2 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.