Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.74 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400709 | 0.81 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL397819 | 0.69 | PTGDR2 (0.78) | PTGDR2PTGDR | |
| SCHEMBL10074104 | 0.68 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL463206 | 0.65 | PTGDR2 (0.74) | PTGDR2 | |
| SCHEMBL1941139 | 0.63 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL14560313 | 0.63 | PTGDR2 (0.51) | PTGDR2PTGDRHTR6 | |
| SCHEMBL6531329 | 0.62 | PTGDR2 (1.00) | PTGDR2PTGDR | |
| SCHEMBL4091943 | 0.59 | KDM4E (0.55) | PTGDR2 | |
| SCHEMBL4103061 | 0.58 | PTGS2 (0.49) | PTGDR2 | |
| SCHEMBL30130273 | 0.57 | KDM4E (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101645-B2 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | ABBOTT LABORATORIES (US) | 2012-01-24 | — | — | US | disclosed |
| US-20090209609-A1 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | ABBVIE INC. | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209609-A1 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | HRH2, HRH1, TSLP | PTGDR2 13/4885PTGDR 30/4885HTR6 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.