SCHEMBL4382331

SCHEMBL4382331

CNC(=O)Nc1cccc(-c2nnnn2S)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.46
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 2/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
PKM P14618 1/20 0.44
KMT2A Q03164 1/20 0.44
MGLL Q99685 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
UBA2 Q9UBT2 1/20 0.43
MAPK14 Q16539 1/20 0.43
CYP17A1 P05093 1/20 0.43
CYP3A4 P08684 1/20 0.43
CCR3 P51677 6/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KDR P35968 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13680542 0.79 CNR1 (0.68) CNR1KDM4EALDH1A1MAPK1POLB
SCHEMBL2632867 0.75 SAE1 (0.68) ALDH1A1MAPK1MAPTSMN1; SMN2PKM
SCHEMBL27589483 0.73 CCR3 (0.53) MAPK14CCR3
SCHEMBL20630845 0.73 PTK2 (0.47) KDM4EALDH1A1POLBMAPTSMN1; SMN2
SCHEMBL1336437 0.72 ALDH1A1 (0.41) KDM4EALDH1A1POLBMAPTSMN1; SMN2
SCHEMBL4772900 0.71 CCR3 (0.52) CCR3
SCHEMBL4605215 0.71 CCR3 (0.60) KMT2ACCR3
SCHEMBL10467082 0.69 ALDH1A1 (0.41) KDM4EALDH1A1POLBMAPTSMN1; SMN2
SCHEMBL26079492 0.69 CCR3 (0.61) CCR3
SCHEMBL13680444 0.69 CNR1 (0.62) CNR1ALDH1A1SMN1; SMN2PKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041433-B1 Heat-developable photosensitive material and method for forming image using the same FUJIFILM CORP (JP) 2009-11-25 EP disclosed
US-6756193-B2 ORGANIC SILVER SALT, REDUCING AGENT AND BINDER FUJI PHOTO FILM CO., LTD. (JP) 2004-06-29 US disclosed
EP-0902322-B1 Thermographic image-recording elements FUJI PHOTO FILM CO LTD (JP) 2003-11-26 EP disclosed
US-6329127-B1 HALOGEN-RELEASING PRECURSOR HAVING AT LEAST ONE DISSOCIATIVE OR HYDROPHILIC SUBSTITUENT AND A SECOND HYDROPHOBIC HALOGEN-RELEASING PRECURSOR; FUJI PHOTO FILM CO., LTD. (JP) 2001-12-11 US disclosed
US-6316172-B1 DEGREE OF WARP AT EDGE FOR LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 2001-11-13 US disclosed
US-20010038977-A1 Heat-developable image-recording material and method for forming image by heat development using same FUJIFILM CORPORATION (JP) 2001-11-08 US disclosed
US-6132950-A A POLYMER LATEX IS USED AS A BINDER IN EACH OF THE IMAGE-FORMING LAYER, THE PROTECTIVE LAYER, AND THE BACK LAYER; MINIMIZED DIMENSIONAL CHANGE BEFORE AND AFTER HEAT DEVELOPMENT, NO WRINKLING OCCURS UPON HEAT DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 2000-10-17 US disclosed
EP-1041433-A1 Heat-developable photosensitive material and method for forming image using the same FUJI PHOTO FILM CO., LTD. (JP) 2000-10-04 EP disclosed
US-6083680-A HIGH IN SENSITIVITY AND HIGH IN CONTRAST, AND CAN PROVIDE AN IMAGE LOW IN DMIN BY UV LIGHT, LIGHT-INSENSITIVE ORGANIC SILVER SALT, A LIGHT-SENSITIVE SILVER HALIDE, FUJI PHOTO FILM CO., LTD. (JP) 2000-07-04 US disclosed
EP-0902322-A1 Thermographic image-recording elements FUJI PHOTO FILM CO., LTD. (JP) 1999-03-17 EP disclosed