Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.62 |
| ▸ | CSF1R | P07333 | 1/20 | 0.60 |
| ▸ | FLT1 | P17948 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.48 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.48 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680542 | 0.89 | CNR1 (0.68) | CNR1CSF1RFLT1FLT3SAE1 | |
| SCHEMBL8265472 | 0.83 | HSD17B10 (0.66) | CNR1CSF1RFLT1FLT3KMT2A | |
| SCHEMBL8906555 | 0.83 | ALDH1A1 (0.60) | CNR1KMT2AALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL13680497 | 0.82 | KIF11 (0.69) | CNR1CSF1RFLT1FLT3KMT2A | |
| SCHEMBL2632867 | 0.81 | SAE1 (0.68) | SAE1UBA2KMT2AALDH1A1PKM | |
| SCHEMBL12444550 | 0.81 | KIF11 (0.61) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13680466 | 0.81 | FAAH (0.56) | CNR1CSF1RFLT1FLT3KMT2A | |
| SCHEMBL13680447 | 0.79 | PNPLA2 (0.62) | CNR1CSF1RFLT1FLT3KMT2A | |
| SCHEMBL5425007 | 0.77 | NPC1 (0.55) | CNR1CSF1RFLT1FLT3KMT2A | |
| SCHEMBL20557956 | 0.77 | CNR1 (1.00) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |