Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480739 | 0.94 | LMNA (0.46) | LMNANAAAXDHGLAHRH3 | |
| SCHEMBL28715109 | 0.87 | LMNA (0.38) | LMNAGLA | |
| SCHEMBL5157531 | 0.81 | NAAA (0.35) | LMNANAAAXDHHRH3 | |
| SCHEMBL7357227 | 0.79 | CAPN1 (0.40) | XDH | |
| SCHEMBL4385037 | 0.79 | HRH3 (0.36) | LMNAGLAHRH3 | |
| SCHEMBL4386652 | 0.79 | HRH3 (0.31) | HRH3 | |
| SCHEMBL4389331 | 0.77 | — | — | |
| SCHEMBL28339640 | 0.77 | NQO1 (0.39) | LMNAGLA | |
| SCHEMBL4381436 | 0.77 | HRH3 (0.36) | LMNAXDHHRH3 | |
| SCHEMBL28686683 | 0.77 | LMNA (0.41) | LMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |