Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.53 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.53 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | IARS1 | P41252 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382762 | 1.00 | LMNA (0.59) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4382768 | 1.00 | LMNA (0.59) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4382469 | 0.93 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4382470 | 0.93 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4382476 | 0.93 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4384638 | 0.90 | LMNA (0.63) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4384642 | 0.90 | LMNA (0.63) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4384643 | 0.90 | LMNA (0.63) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4806275 | 0.89 | LMNA (0.64) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4806268 | 0.89 | LMNA (0.64) | LMNAALDH1A1TP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537135-B1 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS INC (US) | 2009-11-25 | — | — | EP | disclosed |
| US-6914053-B2 | Adenosine A3 receptor agonists | CV THERAPEUTICS, INC. (US) | 2005-07-05 | — | — | US | disclosed |