Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704953 | 0.74 | HRH3 (0.45) | ALDH1A1HRH3CYP2D6MAPT | |
| SCHEMBL18704945 | 0.72 | HTT (0.62) | ALDH1A1HRH3CYP2D6 | |
| SCHEMBL18704962 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HRH3CYP2D6MAPTACKR3 | |
| SCHEMBL25443850 | 0.72 | HRH3 (0.49) | ALDH1A1HRH3CYP2D6 | |
| SCHEMBL18704957 | 0.71 | HTT (0.66) | ALDH1A1HRH3CYP2D6 | |
| SCHEMBL2948497 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HRH3CYP2D6MAPTACKR3 | |
| SCHEMBL12530176 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HRH3CYP2D6MAPTACKR3 | |
| SCHEMBL18087093 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HRH3CYP2D6MAPTACKR3 | |
| SCHEMBL12026487 | 0.71 | ALDH1A1 (0.54) | ALDH1A1HRH3CYP2D6MAPTACKR3 | |
| SCHEMBL18389940 | 0.70 | HRH3 (0.50) | ALDH1A1HRH3CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | ALDH1A1 395/4885HRH3 452/4885CYP2D6 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.