Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382972 | 0.94 | HRH3 (0.56) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL4391299 | 0.89 | HRH3 (0.52) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL4386020 | 0.87 | DRD2 (0.47) | HRH3DRD2DRD4DRD3CHRM2 | |
| SCHEMBL4387729 | 0.86 | HRH3 (0.44) | HRH3DRD2DRD4DRD3CHRM2 | |
| SCHEMBL4384577 | 0.85 | DRD2 (0.45) | HRH3DRD2DRD4DRD3CHRM2 | |
| SCHEMBL4387864 | 0.85 | HRH3 (0.60) | HRH3DRD2DRD4DRD3CHRM2 | |
| SCHEMBL4382010 | 0.85 | HRH3 (0.60) | HRH3DRD2DRD4DRD3CHRM2 | |
| SCHEMBL4383178 | 0.83 | DRD2 (0.42) | HRH3DRD2DRD4DRD3CHRM2 | |
| SCHEMBL4388989 | 0.81 | HRH3 (0.53) | HRH3DRD2DRD4DRD3CHRM2 | |
| SCHEMBL4396105 | 0.80 | HRH3 (0.42) | HRH3DRD2DRD4DRD3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | HRH3 452/4885DRD2 83/4885DRD4 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.