Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610457 | 0.94 | POLB (0.48) | NAAAPOLBRAB9ASMN1; SMN2FFAR4 | |
| SCHEMBL4392999 | 0.86 | ACHE (0.50) | NAAALMNA | |
| SCHEMBL7005662 | 0.84 | MAPT (0.59) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4392025 | 0.81 | ACHE (0.48) | NAAALMNA | |
| SCHEMBL4383589 | 0.81 | ACHE (0.48) | NAAALMNA | |
| SCHEMBL7805719 | 0.79 | MAPT (0.53) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4384265 | 0.79 | ACHE (0.47) | NAAARAB9ALMNA | |
| SCHEMBL11163724 | 0.79 | NPC1 (0.51) | NAAAPOLBRAB9AFFAR4HDAC3 | |
| SCHEMBL11171348 | 0.79 | EPHX1 (0.56) | RAB9ASMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL6651781 | 0.78 | EPHX1 (0.58) | RAB9AHDAC1HDAC2MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |