Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562630 | 0.92 | SMN1; SMN2 (0.42) | HPGDKMT2ASMN1; SMN2SLC40A1ALDH1A1 | |
| SCHEMBL5667982 | 0.88 | KDM4E (0.47) | HPGDKMT2ASMN1; SMN2MEN1SLC40A1 | |
| SCHEMBL4383724 | 0.87 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL4395355 | 0.87 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL4392406 | 0.87 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL2172634 | 0.84 | TRPV1 (0.56) | KMT2AMEN1SLC40A1KDM4EMAPT | |
| SCHEMBL5669715 | 0.84 | HDAC3 (0.43) | KMT2ASMN1; SMN2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL5669968 | 0.84 | CYP1A2 (0.41) | KMT2ASMN1; SMN2MEN1SLC40A1ALDH1A1 | |
| SCHEMBL5667971 | 0.83 | HDAC3 (0.41) | LMNAKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2173905 | 0.83 | SHMT2 (0.43) | HPGDKMT2ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186905-A1 | ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2009-07-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186905-A1 | ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE | ALK, BCL3, MCL1 | EPHX2 1740/4885LMNA 1626/4885HPGD 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.