Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4389505 | 0.89 | PTGIR (0.36) | PTGIRGSK3BCDK2EGFR | |
| SCHEMBL4387719 | 0.88 | L3MBTL1 (0.35) | PTGIRGSK3BEGFRMAPTGSK3A | |
| SCHEMBL4384200 | 0.88 | EGFR (0.38) | PTGIRGSK3BEGFR | |
| SCHEMBL4378282 | 0.87 | PTGIR (0.35) | PTGIRGSK3BEGFR | |
| SCHEMBL4384058 | 0.86 | ADORA2A (0.40) | PTGIREGFR | |
| SCHEMBL4387626 | 0.85 | PTGIR (0.33) | PTGIREGFR | |
| SCHEMBL4379268 | 0.82 | PTGIR (0.42) | PTGIRKCNA5MAPT | |
| SCHEMBL4384051 | 0.82 | GCGR (0.35) | EGFRMAPT | |
| SCHEMBL4384780 | 0.80 | CNR2 (0.40) | EGFRMAPT | |
| SCHEMBL4381492 | 0.79 | PTGIR (0.36) | PTGIREGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538241-B2 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070155813-A1 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| EP-1704856-A1 | HSP90 FAMILY PROTEIN INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155813-A1 | Hsp90 family protein inhibitors | HSP90AB1, HEATR1, HSP90AB2P | PTGIR 2990/4885KCNA5 2912/4885GSK3B 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.