Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379268 | 0.88 | PTGIR (0.42) | PTGIRHSP90AA1HSP90AB1 | |
| SCHEMBL4384125 | 0.87 | PTGIR (0.39) | PTGIRGABRA5HSP90AA1HSP90AB1CYP2C9 | |
| SCHEMBL4389505 | 0.84 | PTGIR (0.36) | PTGIRGABRA5CNR2CYP2C9PTGER4 | |
| SCHEMBL4379839 | 0.84 | ADORA2A (0.35) | PTGIRCNR2 | |
| SCHEMBL4379007 | 0.82 | ADORA2A (0.44) | PTGIRCNR2 | |
| SCHEMBL4392482 | 0.79 | PTGIR (0.36) | PTGIR | |
| SCHEMBL4388328 | 0.79 | GCGR (0.39) | CNR2CYP2C9 | |
| SCHEMBL4393955 | 0.73 | PTGIR (0.39) | PTGIRCNR2HSP90AA1CYP2C9PTGER4 | |
| SCHEMBL4383980 | 0.71 | PTGIR (0.39) | PTGIR | |
| SCHEMBL4392464 | 0.71 | GCGR (0.37) | CNR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538241-B2 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070155813-A1 | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| EP-1704856-A1 | HSP90 FAMILY PROTEIN INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155813-A1 | Hsp90 family protein inhibitors | HSP90AB1, HEATR1, HSP90AB2P | PTGIR 2990/4885GABRA5 785/4885CNR2 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.