SCHEMBL438428

SCHEMBL438428

CCCCCCCCC(=O)Oc1ccc(CN)cc1OC

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.62
TOP2A P11388 1/20 0.60
EPHX2 P34913 1/20 0.56
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C8 P10632 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2B6 P20813 1/20 0.50
CYP2C19 P33261 1/20 0.50
LTA4H P09960 1/20 0.48
TRPV1 Q8NER1 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9895595 0.93 EPHX2 (0.59) ALOX15TOP2AEPHX2CYP1A2CYP3A4
SCHEMBL2815973 0.88 ALOX15 (0.64) ALOX15TOP2AEPHX2CYP1A2CYP3A4
SCHEMBL2817894 0.88 ALOX15 (0.64) ALOX15TOP2AEPHX2CYP1A2CYP3A4
SCHEMBL2815571 0.88 ALOX15 (0.64) ALOX15TOP2AEPHX2CYP1A2CYP3A4
SCHEMBL2817144 0.88 ALOX15 (0.64) ALOX15TOP2AEPHX2CYP1A2CYP3A4
SCHEMBL990700 0.87 EPHX2 (0.58) ALOX15TOP2AEPHX2CYP1A2CYP3A4
SCHEMBL2815756 0.86 ALOX15 (0.65) ALOX15TOP2AEPHX2CYP1A2CYP3A4
SCHEMBL20723822 0.84 PTGS1 (0.64) ALOX15TOP2AEPHX2CYP3A4
SCHEMBL20723797 0.84 PTGS1 (0.64) ALOX15TOP2AEPHX2CYP3A4
SCHEMBL20723701 0.84 PTGS1 (0.64) ALOX15TOP2AEPHX2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2614727-B1 N-Nonanoylvanillylamine as an appetite reduction agent and as a means for generating the feeling of being full and corresponding orally consumable products and method SYMRISE AG (DE) 2016-09-07 EP claimed
EP-2918270-A1 Derivatives of aromatic alkenoic acids for curbing appetite and enhancing mood Symrise AG (DE) 2015-09-16 EP claimed
EP-2614727-A1 N-Nonanoylvanillylamine as an appetite reduction agent, as a means for generating the feeling of being full and as a mood enhancer and corresponding material mixtures, orally consumable products and method Symrise AG (DE) 2013-07-17 EP claimed
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 EP disclosed
CN-117241815-A Composition and method for producing the same 奇华顿股份有限公司 2023-12-15 CN disclosed
CN-116003276-A Method for synthesizing capsaicin by utilizing micro-reaction chip 上海化学试剂研究所有限公司 2023-04-25 CN disclosed
CN-112608247-B Preparation method of capsaicin and capsaicin prepared by using same 遂宁晶安科技有限公司 2023-04-07 CN disclosed
CN-115427002-A Method for producing solid cosmetic and press head 株式会社资生堂 2022-12-02 CN disclosed
CN-115160175-A Preparation method of capsaicin salt 遂宁晶安科技有限公司 2022-10-11 CN disclosed
CN-110305031-B Preparation method of capsaicin and capsaicin prepared by using same 遂宁晶安科技有限公司 2022-07-12 CN disclosed
CN-109689019-B Compositions and products 株式会社资生堂 2022-02-22 CN disclosed
WO-2017220168-A1 CINNAMYL ALCOHOL DERIVATIVE FOR REDUCING APPETITE AND FOR GENERATING THE FEELING OF BEING FULL SYMRISE AG (DE) 2017-12-28 WO disclosed
EP-2614727-B1 N-Nonanoylvanillylamine as an appetite reduction agent and as a means for generating the feeling of being full and corresponding orally consumable products and method SYMRISE AG (DE) 2016-09-07 EP disclosed
EP-2614727-B1 N-Nonanoylvanillylamine as an appetite reduction agent and as a means for generating the feeling of being full and corresponding orally consumable products and method SYMRISE AG (DE) 2016-09-07 EP disclosed
EP-2918270-A1 Derivatives of aromatic alkenoic acids for curbing appetite and enhancing mood Symrise AG (DE) 2015-09-16 EP disclosed
EP-2614727-A1 N-Nonanoylvanillylamine as an appetite reduction agent, as a means for generating the feeling of being full and as a mood enhancer and corresponding material mixtures, orally consumable products and method Symrise AG (DE) 2013-07-17 EP disclosed
EP-2614727-A1 N-Nonanoylvanillylamine as an appetite reduction agent, as a means for generating the feeling of being full and as a mood enhancer and corresponding material mixtures, orally consumable products and method Symrise AG (DE) 2013-07-17 EP disclosed
EP-2614727-A1 N-Nonanoylvanillylamine as an appetite reduction agent, as a means for generating the feeling of being full and as a mood enhancer and corresponding material mixtures, orally consumable products and method Symrise AG (DE) 2013-07-17 EP disclosed
US-20120065221-A1 Extended Release Oral Pharmaceutical Compositions of 3-Hydroxy-N-Methylmorphinan and Method of Use THERAQUEST BIOSCIENCES, INC. (PA) 2012-03-15 US disclosed
CN-1424090-A Chinese medicine preparation for treating toothache and producing method thereof SUO RONGBIN (CN) 2003-06-18 CN disclosed