Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TOP2A | P11388 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817144 | 1.00 | ALOX15 (0.64) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 | |
| SCHEMBL2815571 | 1.00 | ALOX15 (0.64) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 | |
| SCHEMBL2817894 | 1.00 | ALOX15 (0.64) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 | |
| SCHEMBL2815756 | 0.99 | ALOX15 (0.65) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 | |
| SCHEMBL2815127 | 0.94 | ALOX15 (0.59) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 | |
| SCHEMBL2816525 | 0.93 | LTA4H (0.63) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 | |
| SCHEMBL2817244 | 0.89 | ALOX15 (0.62) | ALOX15LTA4H | |
| SCHEMBL438428 | 0.88 | ALOX15 (0.62) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 | |
| SCHEMBL15557423 | 0.87 | ALOX15 (0.72) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 | |
| SCHEMBL15558282 | 0.87 | ALOX15 (0.72) | ALOX15TOP2ACYP1A2CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869822-B2 | Compositions for treatment of dermatological diseases and conditions and methods of use thereof | DermaMedics, LLC (US) | 2020-12-22 | — | — | US | disclosed |
| US-20180235859-A1 | Compositions for Treatment of Dermatological Diseases and Conditions and Methods of Use Thereof | DermaMedics, LLC | 2018-08-23 | — | — | US | disclosed |
| US-9980887-B2 | Compositions for use in treatment of hyperpigmentation and methods of use thereof | DermaMedics, LLC (US) | 2018-05-29 | — | — | US | disclosed |
| EP-3238696-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | Therametics, Llc (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9622950-B2 | Compositions for use in treatment of dermatological diseases and conditions | DermaMedics, LLC (US) | 2017-04-18 | — | — | US | disclosed |
| US-9616006-B2 | Methods and compositions for treating dermatological diseases and conditions | DermaMedics, LLC (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160346180-A1 | Compositions for Use in Treatment of Dermatological Diseases and Conditions and Methods of Use Thereof | DERMAMEDICS LLC (US) | 2016-12-01 | — | — | US | disclosed |
| US-20130289006-A1 | COMPOSITIONS FOR TREATING HYPERPIGMENTATION AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-31 | — | — | US | disclosed |
| US-20130280195-A1 | COMPOSITIONS FOR USE IN TREATMENT OF DERMATOLOGICAL DISEASES AND CONDITIONS AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-24 | — | — | US | disclosed |
| US-20130281411-A1 | COMPOSITIONS FOR TREATING INFLAMMATORY DERMATOLOGICAL DISEASES AND CONDITIONS AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-24 | — | — | US | disclosed |
| US-20130274231-A1 | COMPOSITIONS FOR USE IN TREATMENT OF DERMATOLOGICAL DISEASES AND CONDITIONS | DermaMedics, LLC | 2013-10-17 | — | — | US | disclosed |
| EP-2244690-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | Therametics, Llc (US) | 2010-11-03 | — | — | EP | disclosed |
| US-20100249244-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | THERAMETICS, LLC | 2010-09-30 | — | — | US | disclosed |
| WO-2009049172-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | THERAMETICS, LLC (US) | 2009-04-16 | — | — | WO | disclosed |