Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 17/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387917 | 0.92 | ADORA3 (0.54) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4384606 | 0.80 | ADORA3 (0.52) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4387920 | 0.79 | ADORA3 (0.51) | ADORA3ADORA2AADORA1 | |
| SCHEMBL6384536 | 0.74 | ADORA3 (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4381150 | 0.67 | ADORA3 (1.00) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4381140 | 0.67 | ADORA3 (0.71) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4385169 | 0.67 | ADORA3 (0.74) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4382782 | 0.67 | ADORA3 (0.72) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4394608 | 0.66 | ADORA3 (0.71) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24178186 | 0.65 | ADORA3 (0.62) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537135-B1 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS INC (US) | 2009-11-25 | — | — | EP | disclosed |