Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 17/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384606 | 0.82 | ADORA3 (0.52) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4387920 | 0.81 | ADORA3 (0.51) | ADORA3ADORA2AADORA1 | |
| SCHEMBL25612785 | 0.79 | ADORA3 (0.62) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24178186 | 0.79 | ADORA3 (0.62) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24707891 | 0.79 | ADORA3 (0.62) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL4387917 | 0.75 | ADORA3 (0.54) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4384601 | 0.74 | ADORA3 (0.51) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4387417 | 0.72 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL31061129 | 0.72 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL25566237 | 0.72 | ADORA3 (0.72) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537135-A2 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2005-06-08 | — | — | EP | claimed |
| WO-2004022573-A2 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2004-03-18 | — | — | WO | claimed |