Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580207 | 0.86 | THRB (0.46) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL59813 | 0.85 | POLB (0.56) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL14173142 | 0.85 | POLB (0.56) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL9182829 | 0.84 | THRB (0.51) | POLBHTTTDP1THRBKDM4E | |
| SCHEMBL4384804 | 0.84 | POLB (0.45) | POLBHTTTDP1APEX1THRB | |
| Propane SCHEMBL9476274 | 0.82 | HTT (0.53) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL7894800 | 0.82 | HTT (0.41) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL4453444 | 0.81 | POLB (0.52) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL11965797 | 0.81 | POLB (0.52) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL19770676 | 0.81 | POLB (0.52) | POLBHTTTDP1APEX1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569591-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC Global Technologies B.V. (NL) | 2019-11-20 | — | — | EP | disclosed |
| US-20190337895-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-07 | — | — | US | disclosed |
| US-10435368-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-10-08 | — | — | US | disclosed |
| EP-3172188-B1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-09-04 | — | — | EP | disclosed |
| US-20170166528-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-15 | — | — | US | disclosed |
| EP-3172188-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC Global Technologies B.V. (NL) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016014629-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-01-28 | — | — | WO | disclosed |
| US-7572555-B2 | Hologram recording material, hologram recording method and optical recording medium | FUJIFILM CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20060078803-A1 | Hologram recording material, hologram recording method and optical recording medium | FUJI PHOTO FILM CO., LTD. | 2006-04-13 | — | — | US | disclosed |
| US-5218030-A | Storage stability; chemical and heat resistance, dimensional stability; electronics | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-06-08 | — | — | US | disclosed |
| US-5015555-A | Adhesion, flexibility | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337895-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, HSPBP1 | POLB 973/4885HTT 33/4885TDP1 1173/4885 |
| US-20170166528-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, HSPBP1 | POLB 973/4885HTT 33/4885TDP1 1173/4885 |
| US-10435368-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB1, HSPBP1 | POLB 973/4885HTT 33/4885TDP1 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.