SCHEMBL4384859

SCHEMBL4384859

CC(N)Cc1ccccc1Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.63
SLC6A2 P23975 2/20 0.63
TAAR1 Q96RJ0 2/20 0.63
MAOA P21397 1/20 0.63
SLC6A3 Q01959 1/20 0.63
SIGMAR1 Q99720 1/20 0.63
CYP2A6 P11509 1/20 0.63
ADORA2A P29274 1/20 0.63
ADORA1 P30542 1/20 0.63
HTR2A P28223 2/20 0.52
CYP2D6 P10635 1/20 0.48
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2943661 0.85 SLC6A4 (0.60) SLC6A4SLC6A2TAAR1MAOASLC6A3
SCHEMBL2857779 0.85 SLC6A2 (0.61) SLC6A4SLC6A2TAAR1MAOASLC6A3
SCHEMBL6546971 0.83 HTR2A (0.50) SLC6A4SLC6A2TAAR1MAOASLC6A3
Ortetamine SCHEMBL4381142 0.81 SLC6A4 (0.70) SLC6A4SLC6A2TAAR1MAOASLC6A3
SCHEMBL9468041 0.79 TAAR1 (0.83) SLC6A4SLC6A2TAAR1MAOASLC6A3
SCHEMBL27787183 0.79 SLC6A2 (0.54) SLC6A4SLC6A2TAAR1MAOASLC6A3
SCHEMBL6547503 0.78 HTR2A (0.46) SLC6A4SLC6A2TAAR1MAOASLC6A3
Amphetamine SCHEMBL13746679 0.78 SLC6A2 (1.00) SLC6A4SLC6A2TAAR1MAOASLC6A3
Amphetamine SCHEMBL15094242 0.78 SLC6A2 (1.00) SLC6A4SLC6A2TAAR1MAOASLC6A3
Dextroamphetamine SCHEMBL8859 0.78 SLC6A2 (1.00) SLC6A4SLC6A2TAAR1MAOASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102458543-A Dry powder inhalers 3M INNOVATIVE PROPERTIES CO 2012-05-16 CN claimed
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms Pharmapotheca A, Inc. 2025-07-03 US disclosed
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms Pharmapotheca A Inc. (US) 2025-01-28 US disclosed
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms CHEMAPOTHECA, LLC (US) 2023-10-12 US disclosed
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms Pharmapotheca A, Inc. (US) 2023-08-08 US disclosed
US-11123310-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms PHARMAPOTHECA, LLC (US) 2021-09-21 US disclosed
US-20210030699-A1 Methods of Treatment Using Amphetamine Controlled Release, Prodrug, and Abuse Deterrent Dosage Forms PHARMAPOTHECA, LLC (US) 2021-02-04 US disclosed
US-20200352883-A1 METHODS OF TREATMENT USING AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC (US) 2020-11-12 US disclosed
EP-3478363-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS Chemapotheca LLC (US) 2019-05-08 EP disclosed
US-20180243241-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC 2018-08-30 US disclosed
WO-2017147375-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC (US) 2017-08-31 WO disclosed
CN-102271509-A Novel cyclic benzimidazole derivatives useful anti-diabetic agents 2011-12-07 CN disclosed
CN-102272103-A Isonicotinamide orexin receptor antagonists 2011-12-07 CN disclosed
EP-1062511-B1 IMMUNOASSAYS INVOLVING SURFACE ENHANCED RAMAN SCATTERING UNIV STRATHCLYDE (GB) 2009-11-25 EP disclosed
CN-101420984-A Block degradable polymers and conjugates prepared therefrom NEKTAR THERAPEUTICS AL CORP (US) 2009-04-29 CN disclosed
US-6750065-B1 FOR USE IN DRUG OR EXPLOSIVE DETECTION UNIVERSITY OF STRATHCLYDE (GB) 2004-06-15 US disclosed
CN-1441790-A Enhanced propertied pharmaceuticals ROHM & HAAS (US) 2003-09-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11123310-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 SLC6A4 6/4885SLC6A2 3/4885TAAR1 52/4885
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms SLC6A3, SLC6A2, CES2 SLC6A4 4/4885SLC6A2 2/4885TAAR1 51/4885
US-20200352883-A1 METHODS OF TREATMENT USING AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS SLC6A3, SLC6A2, CES2 SLC6A4 4/4885SLC6A2 2/4885TAAR1 40/4885
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 SLC6A4 6/4885SLC6A2 3/4885TAAR1 37/4885
US-20210030699-A1 Methods of Treatment Using Amphetamine Controlled Release, Prodrug, and Abuse Deterrent Dosage Forms SLC6A3, SLC6A2, CES2 SLC6A4 4/4885SLC6A2 2/4885TAAR1 51/4885
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 SLC6A4 6/4885SLC6A2 3/4885TAAR1 37/4885
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 SLC6A4 6/4885SLC6A2 3/4885TAAR1 52/4885
US-20180243241-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS SLC6A3, CES2, SLC6A2 SLC6A4 6/4885SLC6A2 3/4885TAAR1 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.