SCHEMBL43849

SCHEMBL43849

CC(=O)SC(=O)C(C)N1C(=O)CCC1=O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 2/20 0.40
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15422727 0.82 SLC1A2 (0.33) SLC1A2
SCHEMBL18020563 0.77 SLC1A2 (0.45) SLC1A2CYP2D6CYP2C9MEN1KMT2A
SCHEMBL1564214 0.73 KMT2A (0.53) SLC1A2CYP2D6CYP2C9MEN1KMT2A
SCHEMBL57078 0.73 KMT2A (0.53) SLC1A2CYP2D6CYP2C9MEN1KMT2A
SCHEMBL9182487 0.71 KMT2A (0.49) SLC1A2CYP2D6CYP2C9MEN1KMT2A
SCHEMBL29471924 0.71 SLC1A2 (0.44) SLC1A2CYP2D6CYP2C9MEN1KMT2A
SCHEMBL4522866 0.69 SLC1A2 (0.40) SLC1A2CYP2D6CYP2C9MEN1KMT2A
SCHEMBL3904196 0.69 GLA (0.32)
SCHEMBL5590839 0.68 SLC1A2 (0.45) SLC1A2MEN1KMT2AALDH1A1
Ethylene Glycol SCHEMBL3521351 0.67 SLC1A2 (0.47) SLC1A2CYP2D6CYP2C9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 718 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035410-A1 THERAPEUTIC PEPTIDES AND METHODS OF PEPTIDE DESIGN WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2026-02-05 US claimed
EP-4626462-A1 GLUCOCEREBROSIDASE (GBA) POLYMER CONJUGATE, PREPARATION METHOD AND USE FOR NANOTECHNOLOGICAL BASED ENZYME REPLACEMENT THERAPY Fundació Hospital Universitari Vall Hebron - Institut de Recerca (ES) 2025-10-08 EP claimed
WO-2024115612-A1 GLUCOCEREBROSIDASE (GBA) POLYMER CONJUGATE, PREPARATION METHOD AND USE FOR NANOTECHNOLOGICAL BASED ENZYME REPLACEMENT THERAPY FUNDACIÓ HOSPITAL UNIVERSITARI VALL HEBRON - INSTITUT DE RECERCA (VHIR) (ES) 2024-06-06 WO claimed
US-20230270882-A1 PEPTIDE-NANOPARTICLE CONJUGATES WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-08-31 US claimed
US-11564995-B2 Peptide-nanoparticle conjugates WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-01-31 US claimed
CN-115087465-A Peptide-nanoparticle conjugates 威斯康星校友研究基金会 2022-09-20 CN claimed
US-20210393799-A1 DENDRITIC POLYMERS COMPLEXED WITH IMMUNE CHECKPOINT INHIBITORS FOR ENHANCED CANCER IMMUNOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION 2021-12-23 US claimed
CN-113613680-A Dendrimers complexed with immune checkpoint inhibitors for enhancing cancer immunotherapy 威斯康星校友研究基金会 2021-11-05 CN claimed
US-11125713-B2 Electrochemical sensor for analtye detection CASE WESTERN RESERVE UNIVERSITY (US) 2021-09-21 US claimed
WO-2020092304-A9 DENDRITIC POLYMERS COMPLEXED WITH IMMUNE CHECKPOINT INHIBITORS FOR ENHANCED CANCER IMMUNOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-07-22 WO claimed
WO-2010006604-A1 HIGH CAPACITY SOLID PHASE RADIOMETER MEDICAL APS (DK) 2010-01-21 WO claimed
US-20100003701-A1 COVALENT MODIFICATION AND CONJUGATION OF LUCIFERASE CARDIOGENICS INC. (CA) 2010-01-07 US claimed
EP-2054439-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF INSTITUT PASTEUR (FR) 2009-05-06 EP claimed
WO-2008015273-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF INSTITUT PASTEUR (FR) 2008-02-07 WO claimed
US-20070254311-A1 Covalent modification and conjugation of luciferase CARDIOGENICS INC. (CA) 2007-11-01 US claimed
US-7067322-B2 Fusion protein arrays on metal substrates for surface plasmon resonance imaging WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-06-27 US claimed
WO-2001040306-A9 HUMAN ANTIBODIES AS DETECTION REAGENTS BIOSITE DIAGNOSTICS INC (US) 2002-05-30 WO claimed
EP-0341304-A4 IMPROVED RICIN MOLECULES AND RICIN TOXIN CONJUGATES 1991-01-30 EP claimed
EP-0341304-A1 IMPROVED RICIN MOLECULES AND RICIN TOXIN CONJUGATES GENETICS INSTITUTE, INC. (US) 1989-11-15 EP claimed
WO-1989004839-A1 IMPROVED RICIN MOLECULES AND RICIN TOXIN CONJUGATES GENETICS INSTITUTE, INC. (US) 1989-06-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035410-A1 THERAPEUTIC PEPTIDES AND METHODS OF PEPTIDE DESIGN MICA, IGSF11, TNFSF10 SLC1A2 1535/4885CYP2D6 3754/4885CYP2C9 3014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.