SCHEMBL4522866

SCHEMBL4522866

CC(C(=O)OSSOC(=O)C(C)N1C(=O)CCC1=O)N1C(=O)CCC1=O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 2/20 0.40
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28231228 0.89 SLC1A2 (0.40) SLC1A2KMT2AATMMEN1CYP2D6
SCHEMBL5590839 0.80 SLC1A2 (0.45) SLC1A2KMT2AATMMEN1ALDH1A1
SCHEMBL30327623 0.78 SLC1A2 (0.41) SLC1A2KMT2AATMMEN1CYP2D6
SCHEMBL19031828 0.78 SLC1A2 (0.41) SLC1A2KMT2AATMMEN1ALDH1A1
SCHEMBL5618498 0.77 SLC1A2 (0.39) SLC1A2KMT2AMEN1ALDH1A1
SCHEMBL7259853 0.73 SLC1A2 (0.40) SLC1A2KMT2AATMCYP2D6CYP2C9
SCHEMBL18020563 0.73 SLC1A2 (0.45) SLC1A2KMT2AATMMEN1CYP2D6
SCHEMBL1564214 0.73 KMT2A (0.53) SLC1A2KMT2AATMMEN1CYP2D6
SCHEMBL57078 0.73 KMT2A (0.53) SLC1A2KMT2AATMMEN1CYP2D6
SCHEMBL9182487 0.71 KMT2A (0.49) SLC1A2KMT2AATMMEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115996942-A Macrophage-targeting peptides, conjugates, compositions and uses thereof 双亥生命科学株式会社 2023-04-21 CN claimed
EP-4683674-A1 COMPOSITIONS AND METHODS FOR DELIVERING ANTIBODY OLIGONUCLEOTIDE CONJUGATES FOR EXON SKIPPING Yale University (US) 2026-01-28 EP disclosed
EP-4655007-A1 ANTIBODY OLIGONUCLEOTIDE CONJUGATES Yale University (US) 2025-12-03 EP disclosed
EP-4642488-A1 ANTIBODY DRUG CONJUGATES Yale University (US) 2025-11-05 EP disclosed
WO-2024197302-A1 COMPOSITIONS AND METHODS FOR DELIVERING ANTIBODY OLIGONUCLEOTIDE CONJUGATES FOR EXON SKIPPING YALE UNIVERSITY (US) 2024-09-26 WO disclosed
WO-2024158824-A1 ANTIBODY OLIGONUCLEOTIDE CONJUGATES YALE UNIVERSITY (US) 2024-08-02 WO disclosed
WO-2024145398-A1 ANTIBODY DRUG CONJUGATES YALE UNIVERSITY (US) 2024-07-04 WO disclosed
CN-115996942-A Macrophage-targeting peptides, conjugates, compositions and uses thereof 双亥生命科学株式会社 2023-04-21 CN disclosed
US-11548953-B2 Receptor tyrosine kinase-like orphan receptor 1 (ROR1) single chain Fv antibody fragment conjugates and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-01-10 US disclosed
US-10905775-B2 Particulate constructs for release of active agents CELATOR PHARMACEUTICALS, INC. (US) 2021-02-02 US disclosed
EP-0377649-A1 HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION. HEWLETT PACKARD CO (US) 1990-07-18 EP disclosed
EP-0187894-B1 A SIZE SELECTIVE CATALYST COMPRISING A FIBRIN GEL New York Blood Center, Inc. (US) 1990-04-11 EP disclosed
WO-1989012225-A1 HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION HEWLETT-PACKARD COMPANY (US) 1989-12-14 WO disclosed
US-4652519-A Bifunctional chelating agents and process for their production YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1987-03-24 US disclosed
US-4640778-A NONDEFORMING; UNIFORM PORE SIZE NEW YORK BLOOD CENTER, INC. (US) 1987-02-03 US disclosed
EP-0187894-A1 A size selective catalyst comprising a fibrin gel New York Blood Center, Inc. (US) 1986-07-23 EP disclosed
EP-0085166-B1 A FILTER AND A PROCESS FOR THE PREPARATION THEREOF New York Blood Center, Inc. (US) 1986-06-25 EP disclosed
US-4587018-A Fibrin gel NEW YORK BLOOD CENTER, INC. (US) 1986-05-06 US disclosed
US-4505822-A DIMENSIONAL STABILITY, BLOOD, BACTERIA, VIRUSES, LIPIDS NEW YORK BLOOD CENTER, INC. (US) 1985-03-19 US disclosed
EP-0085166-A1 A filter and a process for the preparation thereof New York Blood Center, Inc. (US) 1983-08-10 EP disclosed