Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385217 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2ATSHRLTA4H | |
| SCHEMBL4385212 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2ATSHRLTA4H | |
| SCHEMBL4387101 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2ATSHRLTA4H | |
| SCHEMBL4387096 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2ATSHRLTA4H | |
| SCHEMBL4387105 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2ATSHRLTA4H | |
| SCHEMBL6925601 | 0.81 | MEN1 (0.59) | ALDH1A1KDM4EKMT2ATSHRLTA4H | |
| SCHEMBL4394790 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4ETSHRLTA4HSMN1; SMN2 | |
| SCHEMBL4394793 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4ETSHRLTA4HSMN1; SMN2 | |
| SCHEMBL4394794 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4ETSHRLTA4HSMN1; SMN2 | |
| SCHEMBL4387289 | 0.80 | CHRM2 (0.39) | KDM4EKMT2ATSHRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-10 | — | — | US | disclosed |
| EP-1889835-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | Daiichi Sankyo Company, Limited (JP) | 2008-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | CBR3, CNR1, C3AR1 | ALDH1A1 2601/4885KDM4E 2035/4885KMT2A 2696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.