Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618792 | 0.84 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EPKMNPSR1 | |
| SCHEMBL6923610 | 0.81 | POLB (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4385212 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4385216 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4385217 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5733825 | 0.79 | L3MBTL1 (0.49) | KMT2AKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5913512 | 0.78 | MAPT (0.67) | MEN1KMT2AKDM4EPKMNPSR1 | |
| SCHEMBL27906266 | 0.78 | TSHR (0.57) | KMT2AKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL22458724 | 0.78 | LTA4H (0.56) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13470311 | 0.76 | MEN1 (0.50) | MEN1KMT2AKDM4EPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |
| EP-0842170-B1 | DIPHENYLMETHYLENE PIPERIDINE DERIVATIVES | AKZO NOBEL NV (NL) | 2001-02-14 | — | — | EP | disclosed |
| US-5935974-A | USED AS DOPAMINE ANTAGONIST FOR TREATMENT OR PROPHYLAXIS OF PSYCHOTIC DISORDERS | AKZO NOBEL, N.V. (NL) | 1999-08-10 | — | — | US | disclosed |
| EP-0842170-A1 | DIPHENYLMETHYLENE PIPERIDINE DERIVATIVES | Akzo Nobel N.V. (NL) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003065-A1 | DIPHENYLMETHYLENE PIPERIDINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 1997-01-30 | — | — | WO | disclosed |