Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 19/20 | 0.85 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.74 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.74 |
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011314 | 0.92 | HTR7 (1.00) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7006812 | 0.92 | HTR7 (1.00) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7006757 | 0.90 | HTR7 (0.87) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7011595 | 0.80 | HTR7 (0.72) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7018008 | 0.79 | HTR7 (0.75) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7005317 | 0.76 | HTR7 (1.00) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4372846 | 0.74 | HTR7 (0.50) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4376845 | 0.74 | HTR7 (0.76) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4380313 | 0.73 | HTR7 (0.76) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4371639 | 0.71 | HTR7 (1.00) | HTR7ADRA1DADRA1AADRA1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280781-B1 | 5-HT 7 RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-18 | — | — | EP | disclosed |