SCHEMBL4385409

SCHEMBL4385409

Cc1cc(F)cc(I)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79108 0.78
SCHEMBL369162 0.78
SCHEMBL812374 0.78
SCHEMBL18335412 0.78
SCHEMBL12156 0.78
SCHEMBL91512 0.78
Ammonia Solution, Strong SCHEMBL28612638 0.76 RAPGEF4 (0.48)
Phosphine SCHEMBL28192310 0.76 CA12 (0.42)
SCHEMBL20662906 0.72 ACHE (0.42)
SCHEMBL23072542 0.71 TTR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038462-A2 INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2025-02-20 WO disclosed
US-20240246969-A1 HETEROCYCLIC DERIVATIVES AS CAMKK2 INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2024-07-25 US disclosed
EP-4337660-A1 HETEROCYCLIC DERIVATIVES AS CAMKK2 INHIBITORS Bristol-Myers Squibb Company (US) 2024-03-20 EP disclosed
CN-117597345-A Heterocyclic derivatives as CaMKK2 inhibitors 百时美施贵宝公司 2024-02-23 CN disclosed
US-11643556-B2 Fluorescent conjugated polymers BECTON, DICKINSON AND COMPANY (US) 2023-05-09 US disclosed
WO-2022240826-A1 HETEROCYCLIC DERIVATIVES AS CAMKK2 INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2022-11-17 WO disclosed
WO-2021129817-A1 PYRIMIDINE-BASED COMPOUND HAVING INHIBITORY EFFECT OF KETOHEXOKINASE (KHK) 南京明德新药研发有限公司 2021-07-01 WO disclosed
EP-3590942-B1 HEPATITIS B VIRUS SURFACE ANTIGEN INHIBITOR FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) 2021-06-09 EP disclosed
US-10859578-B2 Fluorescent methods and materials for directed biomarker signal amplification SKIGEN, INC. (US) 2020-12-08 US disclosed
EP-3712143-A1 QUINAZOLINONE COMPOUND AND APPLICATION THEREOF Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) 2020-09-23 EP disclosed
EP-1409441-B1 INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY MERCK PATENT GMBH (DE) 2009-11-18 EP disclosed
EP-1409441-B1 INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY MERCK PATENT GMBH (DE) 2009-11-18 EP disclosed
CN-100532340-C Indane compounds with negative dielectric anisotropy MERCK PATENT GMBH (DE) 2009-08-26 CN disclosed
US-20070020479-A1 Luminescent-polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-25 US disclosed
US-20070020479-A1 Luminescent-polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-25 US disclosed
US-7122228-B2 Transistros; liquid crystals display; electrooptics MERCK PATENT GMBH (DE) 2006-10-17 US disclosed
US-20040171866-A1 Transistros; liquid crystals display; electrooptics MERCK PATENTGESELLSCHAFT (DE) 2004-09-02 US disclosed
CN-1507427-A Indane compounds with negative dielectric anisotropy Ĭ��ר���ɷ����޹�˾ 2004-06-23 CN disclosed
EP-1409441-A1 INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY MERCK PATENT GmbH (DE) 2004-04-21 EP disclosed
WO-2003010120-A1 INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY MERCK PATENT GMBH (DE) 2003-02-06 WO disclosed