⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482289 | 0.64 | — | — | |
| SCHEMBL28799572 | 0.64 | — | — | |
| Isobutane SCHEMBL8768748 | 0.57 | — | — | |
| SCHEMBL11240395 | 0.56 | ALDH1A1 (0.40) | — | |
| SCHEMBL1107768 | 0.56 | — | — | |
| SCHEMBL432766 | 0.56 | ALDH1A1 (0.30) | — | |
| SCHEMBL4800429 | 0.53 | — | — | |
| SCHEMBL838012 | 0.53 | — | — | |
| SCHEMBL1482597 | 0.53 | — | — | |
| Hydrochloric Acid SCHEMBL5202134 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961019-B | Method for synthesizing aromatic olefin derivative | 天津理工大学 | 2022-08-26 | — | — | CN | claimed |
| CN-112961019-A | Method for simply, conveniently and efficiently synthesizing aromatic olefin derivative | 天津理工大学 | 2021-06-15 | — | — | CN | claimed |
| CN-112961019-B | Method for synthesizing aromatic olefin derivative | 天津理工大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-112961019-A | Method for simply, conveniently and efficiently synthesizing aromatic olefin derivative | 天津理工大学 | 2021-06-15 | — | — | CN | disclosed |
| WO-2015032357-A1 | ZANAMIVIR, ZANAMIVIR INTERMEDIATE, AND SYNTHESIS METHOD | 中国科学院上海有机化学研究所 (CN) | 2015-03-12 | — | — | WO | disclosed |
| US-7629374-B2 | Use of aminoindazole derivatives for the inhibition of tau phosphorylation | AVENTIS PHARMA SA (FR) | 2009-12-08 | — | — | US | disclosed |
| US-7582669-B2 | Aminoindazole derivatives as medicaments and pharmaceutical compositions including them | AVENTIS PHARMA SA (FR) | 2009-09-01 | — | — | US | disclosed |
| US-20080261997-A1 | USE OF AMINOINDAZOLE DERIVATIVES FOR THE INHIBITION OF TAU PHOSPHORYLATION | AVENTIS PHARMA S.A. (FR) | 2008-10-23 | — | — | US | disclosed |
| US-7407981-B2 | Aminoindazole derivatives as medicaments and pharmaceutical compositions including them | AVENTIS PHARMA S.A. (FR) | 2008-08-05 | — | — | US | disclosed |
| US-20070155735-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS INCLUDING THEM | AVENTIS PHARMA S.A. (FR) | 2007-07-05 | — | — | US | disclosed |
| US-20070093479-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS INCLUDING THEM | AVENTIS PHARMA S.A. (FR) | 2007-04-26 | — | — | US | disclosed |
| US-7196109-B2 | Aminoindazole derivatives as medicaments and pharmaceutical compositions including them | AVENTIS PHARMA SA (FR) | 2007-03-27 | — | — | US | disclosed |
| US-7166629-B2 | Aminoindazole derivatives as medicaments and pharmaceutical compositions including them | AVENTIS PHARMA S.A. (FR) | 2007-01-23 | — | — | US | disclosed |
| US-20060074122-A1 | Novel aminoindazole derivatives as medicaments and pharmaceutical compositions including them | AVENTIS PHARMA S.A. (FR) | 2006-04-06 | — | — | US | disclosed |
| US-7019011-B2 | Aminoindazole derivatives as medicaments and pharmaceutical compositions including them | AVENTIS PHARMA S.A. (FR) | 2006-03-28 | — | — | US | disclosed |
| US-20040132794-A1 | Novel aminoindazole derivatives as medicaments and pharmaceutical compositions including them | AVENTIS PHARMA S.A. (FR) | 2004-07-08 | — | — | US | disclosed |
| US-20040110956-A1 | 3-aminoindazole derivatives, e.g., N-butyl-6-chloro-5-phenyl-1H-indazol-3-amine; treating diseases involving phosphorylation of the tau protein such as Alzheimer's disease, Parkinson's disease, and frontoparietal dementia | AVENTIS PHARMA S.A. (FR) | 2004-06-10 | — | — | US | disclosed |