SCHEMBL4386437

SCHEMBL4386437

O=C(Oc1ccccc1C(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.73
LMNA P02545 2/20 0.73
SLC6A3 Q01959 1/20 0.70
KMT2A Q03164 7/20 0.65
HSD17B10 Q99714 5/20 0.65
TSHR P16473 1/20 0.65
MAPT P10636 7/20 0.58
HPGD P15428 2/20 0.58
ALOX15 P16050 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
KDM4E B2RXH2 3/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
TDP1 Q9NUW8 3/20 0.54
PARP10 Q53GL7 1/20 0.54
GAA P10253 2/20 0.52
PTGS2 P35354 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
PKM P14618 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7769807 0.90 ALDH1A1 (0.62) ALDH1A1LMNASLC6A3KMT2AHSD17B10
SCHEMBL28263594 0.87 HSD17B10 (0.72) ALDH1A1LMNASLC6A3KMT2AHSD17B10
SCHEMBL1282647 0.85 HSD17B10 (0.64) ALDH1A1LMNASLC6A3KMT2AHSD17B10
SCHEMBL5710896 0.85 HSD17B10 (0.64) ALDH1A1LMNASLC6A3KMT2AHSD17B10
SCHEMBL1870544 0.84 PARP10 (0.70) ALDH1A1LMNAKMT2AHSD17B10TSHR
SCHEMBL31888 0.84 PARP10 (0.70) ALDH1A1LMNAKMT2AHSD17B10TSHR
SCHEMBL8369356 0.84 HSD17B10 (0.83) ALDH1A1LMNASLC6A3KMT2AHSD17B10
SCHEMBL14152348 0.84 HSD17B10 (0.62) ALDH1A1LMNASLC6A3KMT2AHSD17B10
SCHEMBL6948356 0.84 SLC6A3 (0.72) ALDH1A1LMNASLC6A3KMT2AHSD17B10
SCHEMBL4392121 0.84 HSD17B10 (0.62) ALDH1A1LMNASLC6A3KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56024481-A None JP disclosed
US-7576036-B2 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJIFILM CORPORATION (JP) 2009-08-18 US disclosed
US-20080171143-A1 Process For Preparation Of Optical Compensatory Sheet FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
US-20070032381-A1 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2007-02-08 US disclosed
US-7011922-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-03-14 US disclosed
US-20050272604-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-12-08 US disclosed
US-20050260518-A1 Heat sensitive recording material and microcapsule FUJI PHOTO FILM CO., LTD. 2005-11-24 US disclosed
EP-1598206-A2 Heat sensitive recording material and microcapsule FUJI PHOTO FILM CO., LTD. (JP) 2005-11-23 EP disclosed
EP-1598208-A2 Heat-sensitive recording material Fuji Photo Film Co., Ltd. (JP) 2005-11-23 EP disclosed
US-6919297-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2005-07-19 US disclosed
US-4609928-A LEUCO DYES, COLOR DEVELOPERS, BISHENOL, P-HYDROXYBENZOIC ACID ESTER, POROSITY, FILLERS RICOH COMPANY, LTD. (JP) 1986-09-02 US disclosed
US-4575734-A LEVCO DYES RICOH COMPANY, LTD. (JP) 1986-03-11 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4561000-A METHINE-TYPE CHROMOGEN, BENZOQUINONE OXIDIZER, COLOR PRODUCTION SENSITIVITY REGULATOR, SUBSTRATE MITSUI TOATSU CHEMICALS, INC. (JP) 1985-12-24 US disclosed
US-4547788-A SHEET HAVING LAYER CONTAINING LEVCO DYE; ACCEPTOR SHEET CONTAININGCOLORING AGENT; POROUS FILLER RICOH COMPANY, LTD. (JP) 1985-10-15 US disclosed
US-4393258-A LIQUID CRYSTALS DAINIPPON MK & CHEMICALS INC. (JP) 1983-07-12 US disclosed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US disclosed
JP-S5624481-A LIQUID CRYSTAL COMPOSITION SEIKO EPSON CORP 1981-03-09 JP disclosed
US-4237026-A Liquid crystalline carboxylic acid esters MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-12-02 US disclosed
US-4011173-A MODIFIED NEMATIC MIXTURES WITH POSITIVE DIELECTRIC ANISOTROPY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-03-08 US disclosed