Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545400 | 0.81 | KDM4E (0.50) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL8667894 | 0.78 | TP53 (0.52) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL17977217 | 0.74 | KDM4E (0.48) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL2548432 | 0.74 | KDM4E (0.48) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL18124095 | 0.74 | KDM4E (0.48) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL22605710 | 0.73 | MAPK1 (0.57) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL25214672 | 0.73 | KDM4E (0.47) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL1902496 | 0.70 | KDM4E (0.47) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL8667981 | 0.70 | KDM4E (0.47) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL311155 | 0.70 | HPGD (0.55) | GPR119KDM4EMAPTTHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | GPR119 1988/4885TP53 2329/4885KDM4E 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.