SCHEMBL311155

SCHEMBL311155

CC(C)(C)OC(=O)N1CCC(C#N)CC1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.55
RECQL P46063 1/20 0.53
EPHX1 P07099 1/20 0.53
USP2 O75604 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GPR119 Q8TDV5 9/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 1/20 0.50
DPP4 P27487 1/20 0.50
KDM4E B2RXH2 1/20 0.48
THRB P10828 1/20 0.48
PTPN2 P17706 1/20 0.48
PTPN1 P18031 1/20 0.48
PTPN6 P29350 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23727584 0.94 HPGD (0.57) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL1980161 0.94 HPGD (0.50) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL12205292 0.94 HPGD (0.57) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL13820 0.92 MAPT (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL1968766 0.92 MAPT (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL56905 0.92 MAPT (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL2087178 0.91 HPGD (0.48) HPGDRECQLEPHX1USP2SMN1; SMN2
Hydrochloric Acid SCHEMBL3937411 0.89 MAPT (0.47) HPGDRECQLEPHX1USP2SMN1; SMN2
Piperidine SCHEMBL2684524 0.88 HPGD (0.52) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL31209769 0.87 MAPT (0.47) HPGDRECQLEPHX1USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514811-A Synthesis method of 2, 7-diaza-spiro [3,5] nonane-2-tert-butyl formate 药璞(上海)医药科技有限公司 2023-08-01 CN claimed
CN-113024530-B Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof 合肥工业大学 2023-07-18 CN claimed
CN-113024530-A Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof 合肥工业大学 2021-06-25 CN claimed
CN-107646855-B Application of thiazole compound containing piperidine in preparation of bactericide and preparation method thereof 浙江工业大学 2020-07-07 CN claimed
EP-4027995-B1 HPK1 ANTAGONISTS AND USES THEREOF NIMBUS SATURN INC (US) 2026-05-27 EP disclosed
CN-116546990-B CD73 inhibitor and pharmaceutical application thereof RISEN (SUZHOU) PHARMA TECH Co.,Ltd. (CN) 2026-05-26 CN disclosed
EP-4743078-A2 APOL1 INHIBITORS AND METHODS OF USE Maze Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-3746436-B1 FUSED RING COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-05-20 EP disclosed
US-20260132259-A1 COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, ARTICLE, AND METHOD FOR MANUFACTURING ARTICLE AGC Inc. (JP) 2026-05-14 US disclosed
US-20260124214-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LIMITED (GB) 2026-05-07 US disclosed
US-20260116881-A1 KIF MODULATOR COMPOUNDS AND METHODS OF USE IAMBIC THERAPEUTICS INC (US) 2026-04-30 US disclosed
EP-4714446-A2 PHARMACEUTICAL COMPOUNDS Nxera Pharma UK Limited (GB) 2026-03-25 EP disclosed
WO-2000076972-A1 N-CYCLOPENTYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-12-21 WO disclosed
WO-2000059502-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 WO disclosed
WO-2000039125-A1 PIPERIDINES AS CCR5 MODULATORS PFIZER LIMITED (GB) 2000-07-06 WO disclosed
EP-1002794-A1 4-[(Aryl)(aryloxy)methyl]piperidine derivatives and their use as serotonin and/or noradrenaline reuptake inhibitors FAES, Fabrica Espanola de Productos Quimicos y Farmaceuticos, S.A. (ES) 2000-05-24 EP disclosed
EP-0944388-A2 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 1999-09-29 EP disclosed
US-5891889-A Inhibitors of farnesyl-protein transferase MERCK & CO., INC. (US) 1999-04-06 US disclosed
WO-1997038665-A2 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1997-10-23 WO disclosed
US-4760158-A Cyclic halonitriles JOHN WYETH & BROTHER LIMITED (GB) 1988-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116881-A1 KIF MODULATOR COMPOUNDS AND METHODS OF USE KIF2C, KIF5B, KIF5C HPGD 4099/4885RECQL 382/4885EPHX1 4528/4885
US-20260124214-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER CBR1, NR3C1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 HPGD 1203/4885RECQL 1812/4885EPHX1 1118/4885
US-20260132259-A1 COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, ARTICLE, AND METHOD FOR MANUFACTURING ARTICLE MSR1, SEM1, TAS2R1 HPGD 4864/4885RECQL 342/4885EPHX1 2625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.