SCHEMBL4386775

SCHEMBL4386775

CC(CNCCCN)NCCCN

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.46
CA6 P23280 5/20 0.46
CA7 P43166 5/20 0.46
CA9 Q16790 5/20 0.46
CA14 Q9ULX7 5/20 0.46
CA5B Q9Y2D0 5/20 0.46
CA2 P00918 4/20 0.46
CA4 P22748 4/20 0.46
CA5A P35218 4/20 0.46
ALOX15 P16050 3/20 0.46
CASP2 P42575 2/20 0.46
F13A1 P00488 2/20 0.46
CYP1A2 P05177 2/20 0.46
THPO P40225 2/20 0.46
MEN1 O00255 2/20 0.46
RECQL P46063 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2C19 P33261 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA3 P07451 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16260099 0.96 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL11831004 0.89 RELA (0.44) CA12CA6CA7CA9CA14
SCHEMBL4385746 0.86 CA12 (0.43) CA12CA6CA7CA9CA14
SCHEMBL9943430 0.85 CA12 (0.41) CA12CA6CA7CA9CA14
SCHEMBL22043446 0.85 CYP2C19 (0.45) CA12CA6CA7CA9CA14
SCHEMBL6891737 0.82 CA12 (0.52) CA12CA6CA7CA9CA14
SCHEMBL7063715 0.81 TDP1 (0.37) CA12CA6CA7CA9CA14
SCHEMBL25003626 0.80 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL6217773 0.80 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL1556475 0.79 TSHR (0.46) CA12CA7CA14CA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3706439-B1 RESIN COMPOSITION FOR ACOUSTIC MATCHING LAYER, CURED PRODUCT, ACOUSTIC MATCHING SHEET, ACOUSTIC WAVE PROBE, ACOUSTIC WAVE MEASUREMENT DEVICE, PRODUCTION METHOD FOR ACOUSTIC WAVE PROBE, AND MATERIALS SET FOR ACOUSTIC MATCHING LAYER FUJIFILM CORP (JP) 2024-03-13 EP disclosed
US-11891505-B2 Resin composition for acoustic matching layer, cured product, acoustic matching sheet, acoustic probe, acoustic measuring apparatus, method for producing acoustic probe, and acoustic matching layer material set FUJIFILM CORPORATION (JP) 2024-02-06 US disclosed
EP-3706439-A1 RESIN COMPOSITION FOR ACOUSTIC MATCHING LAYER, CURED PRODUCT, ACOUSTIC MATCHING SHEET, ACOUSTIC WAVE PROBE, ACOUSTIC WAVE MEASUREMENT DEVICE, PRODUCTION METHOD FOR ACOUSTIC WAVE PROBE, AND MATERIALS SET FOR ACOUSTIC MATCHING LAYER FUJIFILM Corporation (JP) 2020-09-09 EP disclosed
US-20200270448-A1 RESIN COMPOSITION FOR ACOUSTIC MATCHING LAYER, CURED PRODUCT, ACOUSTIC MATCHING SHEET, ACOUSTIC PROBE, ACOUSTIC MEASURING APPARATUS, METHOD FOR PRODUCING ACOUSTIC PROBE, AND ACOUSTIC MATCHING LAYER MATERIAL SET FUJIFILM CORPORATION (JP) 2020-08-27 US disclosed
EP-1017275-B1 POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS MURPHY MICHAEL A (US) 2009-11-25 EP disclosed
US-6576672-B1 Parkingson's Disease and dementias characterized by mito-chondrial damage; such as 3,7-diazanonane-1,9-diamine; neutralizing dopamine depriving effect MURPHY MICHAEL A (US) 2003-06-10 US disclosed
EP-1017275-A4 POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS MURPHY MICHAEL A (US) 2002-12-18 EP disclosed
EP-1017275-A1 POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS Murphy, Michael A. (US) 2000-07-12 EP disclosed
US-5906996-A Tetramine treatment of neurological disorders MURPHY MICHAEL A (US) 1999-05-25 US disclosed
WO-1999008519-A1 POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS MURPHY MICHAEL A (US) 1999-02-25 WO disclosed
US-5296598-A Derivatives of 2,4-diamino-1,3,5-triazinyl-6-phosphonic acid MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) 1994-03-22 US disclosed
US-4764537-A KETIMINE, ALDIMINE, ENAMINE OR CYCLIC SCHIFF BASE, METAL SALT OF CARBOXYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 1988-08-16 US disclosed
US-4163754-A Fluorinated sulfonamides ICI AMERICAS INC. (US) 1979-08-07 US disclosed