Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA6 | P23280 | 5/20 | 0.43 |
| ▸ | CA7 | P43166 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA4 | P22748 | 4/20 | 0.41 |
| ▸ | CA5A | P35218 | 4/20 | 0.41 |
| ▸ | CA3 | P07451 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405494 | 0.87 | MEN1 (0.31) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4386775 | 0.86 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4542114 | 0.84 | ANPEP (0.39) | CA12CA6CA7CA9CA14 | |
| SCHEMBL16260099 | 0.82 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL18814474 | 0.80 | GGT1 (0.38) | MEN1RECQLKMT2AALOX15LMNA | |
| SCHEMBL16335714 | 0.80 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL22043448 | 0.76 | — | — | |
| SCHEMBL11831004 | 0.76 | RELA (0.44) | CA12CA6CA7CA9CA14 | |
| SCHEMBL22043446 | 0.76 | CYP2C19 (0.45) | CA12CA6CA7CA9CA14 | |
| SCHEMBL9943430 | 0.76 | CA12 (0.41) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017275-B1 | POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS | MURPHY MICHAEL A (US) | 2009-11-25 | — | — | EP | disclosed |
| US-6673890-B1 | DETERGENTS, DISPERSANTS | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-06 | — | — | US | disclosed |
| EP-1198492-B1 | ZWITTERIONIC POLYAMINES AND A PROCESS FOR THEIR PRODUCTION | BASF AG (DE) | 2003-10-08 | — | — | EP | disclosed |
| US-6576672-B1 | Parkingson's Disease and dementias characterized by mito-chondrial damage; such as 3,7-diazanonane-1,9-diamine; neutralizing dopamine depriving effect | MURPHY MICHAEL A (US) | 2003-06-10 | — | — | US | disclosed |
| EP-1017275-A4 | POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS | MURPHY MICHAEL A (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1017275-A1 | POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS | Murphy, Michael A. (US) | 2000-07-12 | — | — | EP | disclosed |
| US-5906996-A | Tetramine treatment of neurological disorders | MURPHY MICHAEL A (US) | 1999-05-25 | — | — | US | disclosed |
| WO-1999008519-A1 | POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS | MURPHY MICHAEL A (US) | 1999-02-25 | — | — | WO | disclosed |
| US-5059391-A | USE OF POLYARALKYLAMINES AS CORROSION INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-22 | — | — | US | disclosed |
| EP-0306831-B1 | USE OF POLYARALKYL AMINES AS CORROSION INHIBITORS | BAYER AG (DE) | 1991-07-03 | — | — | EP | disclosed |
| US-4902830-A | CORROSION INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-20 | — | — | US | disclosed |
| EP-0306831-A1 | Use of polyaralkyl amines as corrosion inhibitors | BAYER AG (DE) | 1989-03-15 | — | — | EP | disclosed |
| US-4163754-A | Fluorinated sulfonamides | ICI AMERICAS INC. (US) | 1979-08-07 | — | — | US | disclosed |