Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2999872 | 0.98 | FAAH (0.47) | FAAHMEN1HTTKMT2ACNR2 | |
| SCHEMBL4391954 | 0.96 | FAAH (0.45) | FAAHMEN1HTTKMT2ACNR2 | |
| SCHEMBL3005497 | 0.94 | FAAH (0.46) | FAAHMEN1HTTKMT2ACNR2 | |
| SCHEMBL3006284 | 0.94 | FAAH (0.46) | FAAHMEN1HTTKMT2ACNR2 | |
| SCHEMBL3000962 | 0.94 | CNR2 (0.41) | FAAHMEN1KMT2ACNR2PLA2G2A | |
| SCHEMBL3006611 | 0.94 | FAAH (0.46) | FAAHMEN1HTTKMT2ACNR2 | |
| SCHEMBL3006187 | 0.91 | CNR2 (0.41) | FAAHMEN1KMT2ACNR2TP53 | |
| SCHEMBL3005482 | 0.91 | CNR2 (0.42) | FAAHKMT2ACNR2TP53UBE2M | |
| SCHEMBL4381898 | 0.90 | FAAH (0.43) | FAAHMEN1HTTKMT2ACNR2 | |
| SCHEMBL3008931 | 0.90 | POLB (0.44) | FAAHKMT2ACNR2TP53UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049520-A2 | INDOLE COMPOUNDS | Ironwood Pharmaceuticals, Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008019357-A2 | INDOLE COMPOUNDS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-02-14 | — | — | WO | disclosed |