SCHEMBL4386933

SCHEMBL4386933

CC(=O)CC(=O)Nc1ccc(C(=O)O)c(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C19 P33261 1/20 0.53
HIF1A Q16665 1/20 0.53
MAPT P10636 1/20 0.51
CYP3A4 P08684 1/20 0.51
TSHR P16473 2/20 0.48
CASP1 P29466 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HPGD P15428 2/20 0.46
LMNA P02545 2/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA7 P43166 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552041 0.88 KDM4E (0.57) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL28332744 0.88 MEN1 (0.53) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL1304698 0.83 RORC (0.54) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL9824009 0.83 CYP3A4 (0.72) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL7529550 0.83 KMT2A (0.56) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL4385068 0.83 POLB (0.57) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL27664708 0.82 ADORA2A (0.60) MEN1KMT2AMAPTCYP3A4TSHR
SCHEMBL28504512 0.81 KMT2A (0.53) ALDH1A1MEN1KMT2AKDM4ECYP1A2
SCHEMBL14513157 0.81 SMN1; SMN2 (0.50) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL12531500 0.81 HPGD (0.68) ALDH1A1MEN1KMT2AKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009069314-A2 PIGMENT COMPOSITION, AND POLYMERIZED TONER TOYO INK MFG. CO., LTD. (JP) 2009-06-04 WO disclosed
US-4474609-A Recrystallization-resistant monoazo pigment mixtures of high tinctorial strength, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-02 US disclosed
EP-0012944-B1 COLOUR-FAST MONOAZO PIGMENT MIXTURES STABLE AGAINST RECRYSTALLISATION, PROCESS FOR THEIR PREPARATION AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-23 EP disclosed
EP-0012944-A1 Colour-fast monoazo pigment mixtures stable against recrystallisation, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed