Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913865 | 0.86 | MEN1 (0.61) | CYP3A4LMNAGAAALDH1A1MEN1 | |
| SCHEMBL12531500 | 0.86 | HPGD (0.68) | CYP3A4LMNAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL6023089 | 0.85 | NPC1 (0.71) | CYP3A4LMNAGAAALDH1A1MEN1 | |
| SCHEMBL7098921 | 0.84 | CYP3A4 (0.69) | CYP3A4EPHX1EPHX2LMNAGAA | |
| Propanil SCHEMBL21900164 | 0.84 | CYP3A4 (1.00) | CYP3A4EPHX1EPHX2LMNAL3MBTL1 | |
| Propanil SCHEMBL26871 | 0.84 | CYP3A4 (1.00) | CYP3A4EPHX1EPHX2LMNAL3MBTL1 | |
| Propanil SCHEMBL1702271 | 0.84 | CYP3A4 (1.00) | CYP3A4EPHX1EPHX2LMNAL3MBTL1 | |
| SCHEMBL2552041 | 0.83 | KDM4E (0.57) | CYP3A4GAAALDH1A1MEN1KMT2A | |
| SCHEMBL28332744 | 0.83 | MEN1 (0.53) | CYP3A4LMNAGAAALDH1A1MEN1 | |
| SCHEMBL4386933 | 0.83 | ALDH1A1 (0.53) | CYP3A4LMNAGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200134-B1 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4902715-A | Fungicidal 4-monohaloacetoacetoacetanilides | THE DOW CHEMICAL COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4736038-A | IMMUNOLOGY | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| EP-0200134-A2 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |