Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043200 | 0.81 | CYP2A6 (0.52) | CYP2A6MAOBMAOAKDM4EFLT3 | |
| SCHEMBL28909940 | 0.78 | KDM4E (0.47) | CYP2A6MAOBMAOAKDM4EFLT3 | |
| SCHEMBL3264168 | 0.78 | CYP2A6 (0.43) | CYP2A6MAOBMAOAKDM4EFLT3 | |
| SCHEMBL28311733 | 0.78 | CYP2A6 (0.43) | CYP2A6MAOBMAOAKDM4EFLT3 | |
| SCHEMBL10373052 | 0.76 | TNKS (0.46) | MAOBKDM4ETDP1SMN1; SMN2HPGD | |
| SCHEMBL17785118 | 0.75 | CYP2D6 (0.49) | CYP2A6MAOBMAOAKDM4EFLT3 | |
| SCHEMBL225144 | 0.72 | CYP2A6 (0.64) | CYP2A6MAOBMAOAKDM4EFLT3 | |
| SCHEMBL23615788 | 0.72 | CYP2D6 (0.46) | CYP2A6MAOBMAOAKDM4EFLT3 | |
| SCHEMBL17969087 | 0.71 | CYP2D6 (0.49) | CYP2A6MAOBMAOAKDM4EFLT3 | |
| SCHEMBL9811903 | 0.71 | CYP2D6 (0.49) | CYP2A6MAOBMAOAKDM4EFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021381-B1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-8580976-B2 | Process for preparing A 2-substituted benzofuran-3-yl borate ester | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130102789-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102795-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130085284-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-04 | — | — | US | disclosed |
| US-8362265-B2 | Hafnium complexes of heterocyclic organic ligands | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-01-29 | — | — | US | disclosed |
| US-20090069567-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC | 2009-03-12 | — | — | US | disclosed |
| EP-2021381-A2 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007130242-A2 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102795-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | CYP2A6 814/4885MAOB 165/4885MAOA 206/4885 |
| US-20130085284-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | CYP2A6 814/4885MAOB 165/4885MAOA 206/4885 |
| US-20090069567-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | CYP2A6 814/4885MAOB 165/4885MAOA 206/4885 |
| US-20130102789-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | CYP2A6 814/4885MAOB 165/4885MAOA 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.