Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142288 | 0.78 | SMN1; SMN2 (0.51) | CYP2A6FLT3POLBSMN1; SMN2CA2 | |
| SCHEMBL28311733 | 0.78 | CYP2A6 (0.43) | CYP2A6FLT3LOXL2POLBSMN1; SMN2 | |
| SCHEMBL28909940 | 0.78 | KDM4E (0.47) | CYP2A6FLT3LOXL2POLBSMN1; SMN2 | |
| SCHEMBL4386949 | 0.78 | CYP2A6 (0.43) | CYP2A6FLT3LOXL2POLBSMN1; SMN2 | |
| SCHEMBL5960700 | 0.77 | FLT3 (0.49) | FLT3SMN1; SMN2CA2KDM4EHSD17B10 | |
| SCHEMBL7538814 | 0.76 | KDM4E (0.49) | POLBSMN1; SMN2CA2KDM4ETDP1 | |
| SCHEMBL28457667 | 0.75 | ALDH1A1 (0.49) | FLT3LOXL2POLBSMN1; SMN2CA2 | |
| SCHEMBL29793846 | 0.75 | ALDH1A1 (0.49) | FLT3LOXL2POLBSMN1; SMN2CA2 | |
| SCHEMBL12087087 | 0.75 | ALDH1A1 (0.49) | FLT3LOXL2POLBSMN1; SMN2CA2 | |
| SCHEMBL9811903 | 0.75 | CYP2D6 (0.49) | CYP2A6FLT3LOXL2POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216259-B1 | TRIAZINE DERIVATIVES, A PROCESS FOR PREPARATION OF THE DERIVATIVES, AND HERBICIDES CONTAINING THE DERIVATIVES AS THE EFFECTIVE COMPONENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-02-28 | — | — | EP | claimed |
| EP-0216259-A1 | Triazine derivatives, a process for preparation of the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-04-01 | — | — | EP | claimed |
| US-20230183199-A1 | 2-AMINOINDANE COMPOUNDS FOR MENTAL DISORDERS OR ENHANCEMENT | TACTOGEN INC. (US) | 2023-06-15 | — | — | US | disclosed |
| EP-4192447-A1 | 2-AMINOINDANE COMPOUNDS FOR MENTAL DISORDERS OR ENHANCEMENT | Tactogen Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-116209657-A | 2-aminoindane compounds for mental disorders or enhancement | 泰科根公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-116075300-A | Advantageous benzofuran compositions for mental disorders or mental enhancement | 泰科根公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-2108649-B1 | Novel indol carboxylic acid bispyridyl carboxamide derivatives as 5-HT2c receptor antagonists | KOREA RES INST CHEM TECH (KR) | 2013-04-24 | — | — | EP | disclosed |
| US-8324246-B2 | Indol carboxylic acid bispyridyl carboxamide derivatives, pharmaceutically acceptable salt thereof, preparation method and composition containing the same as an active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-12-04 | — | — | US | disclosed |
| EP-1335907-B1 | PIPERAZINYLPYRAZINE COMPOUNDS AS AGONIST OR ANTAGONIST OF SEROTONIN 5HT-2 RECEPTOR | BIOVITRUM AB PUBL (SE) | 2010-06-09 | — | — | EP | disclosed |
| EP-1513831-B1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB PUBL (SE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2009125923-A2 | NOVEL INDOL CARBOXYLIC ACID BISPYRIDYL CARBOXAMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD AND COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-10-15 | — | — | WO | disclosed |
| EP-0216259-B1 | TRIAZINE DERIVATIVES, A PROCESS FOR PREPARATION OF THE DERIVATIVES, AND HERBICIDES CONTAINING THE DERIVATIVES AS THE EFFECTIVE COMPONENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4740230-A | Triazine derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-04-26 | — | — | US | disclosed |
| EP-0216259-A1 | Triazine derivatives, a process for preparation of the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0029311-B1 | AMINOALKYL BENZOFURAN DERIVATIVES, THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1985-01-23 | — | — | EP | disclosed |
| EP-0029311-A1 | Aminoalkyl benzofuran derivatives, their production and compositions containing them | MERCK & CO. INC. (US) | 1981-05-27 | — | — | EP | disclosed |
| EP-0029311-A1 | Aminoalkyl benzofuran derivatives, their production and compositions containing them | MERCK & CO. INC. (US) | 1981-05-27 | — | — | EP | disclosed |
| US-4238487-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4238487-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4238487-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183199-A1 | 2-AMINOINDANE COMPOUNDS FOR MENTAL DISORDERS OR ENHANCEMENT | AADAT, SLC1A2, TPH2 | CYP2A6 941/4885FLT3 4195/4885LOXL2 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.