Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382488 | 0.77 | CYP19A1 (0.37) | CYP19A1 | |
| SCHEMBL10639556 | 0.75 | POLB (0.45) | CYP19A1POLB | |
| SCHEMBL9123280 | 0.70 | CYP19A1 (0.56) | CYP19A1 | |
| SCHEMBL8114777 | 0.70 | ESR1 (0.33) | — | |
| SCHEMBL10639995 | 0.69 | POLB (0.40) | CYP19A1POLB | |
| SCHEMBL9120812 | 0.68 | CYP19A1 (0.58) | CYP19A1 | |
| SCHEMBL9120738 | 0.68 | CYP19A1 (0.58) | CYP19A1 | |
| SCHEMBL9121148 | 0.66 | CYP19A1 (0.60) | CYP19A1 | |
| SCHEMBL9124189 | 0.65 | CYP19A1 (0.55) | CYP19A1 | |
| SCHEMBL633241 | 0.62 | GRIN2D (0.39) | CYP19A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |