Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114777 | 0.81 | ESR1 (0.33) | SLC6A3SLC6A2 | |
| SCHEMBL4387280 | 0.77 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL9120738 | 0.72 | CYP19A1 (0.58) | CYP19A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4382483 | 0.71 | CYP19A1 (0.40) | CYP19A1SLC6A4SLC6A3 | |
| SCHEMBL8115694 | 0.71 | SHBG (0.37) | — | |
| SCHEMBL9728037 | 0.70 | CYP19A1 (0.55) | CYP19A1 | |
| SCHEMBL9121148 | 0.70 | CYP19A1 (0.60) | CYP19A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9124189 | 0.69 | CYP19A1 (0.55) | CYP19A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4381403 | 0.69 | ESR1 (0.34) | CYP19A1 | |
| SCHEMBL9123280 | 0.69 | CYP19A1 (0.56) | CYP19A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | claimed |
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |