Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31193267 | 0.84 | HPGD (0.47) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL26926046 | 0.82 | KDM4E (0.45) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL29264358 | 0.82 | EPHX1 (0.46) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL30731919 | 0.82 | KDM4E (0.45) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL7581179 | 0.82 | EPHX1 (0.46) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL26926233 | 0.82 | KDM4E (0.45) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL30731986 | 0.82 | KDM4E (0.45) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL26926054 | 0.82 | KDM4E (0.45) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL1997815 | 0.80 | HPGD (0.54) | HPGDEPHX1KDM4EPKMRECQL | |
| SCHEMBL4093887 | 0.80 | HPGD (0.57) | HPGDEPHX1KDM4EPKMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | HPGD 349/4885EPHX1 2060/4885KDM4E 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.