Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581179 | 1.00 | EPHX1 (0.46) | EPHX1HPGDKDM4EPKMRECQL | |
| SCHEMBL7582245 | 0.96 | EPHX1 (0.48) | EPHX1HPGDKDM4EPKMRECQL | |
| SCHEMBL29264338 | 0.83 | LTA4H (0.43) | KDM4ECNR1CNR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL29264336 | 0.83 | LTA4H (0.43) | KDM4ECNR1CNR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL4387757 | 0.82 | HPGD (0.49) | EPHX1HPGDKDM4EPKMRECQL | |
| SCHEMBL31193267 | 0.80 | HPGD (0.47) | EPHX1HPGDKDM4EPKMRECQL | |
| SCHEMBL17001789 | 0.78 | EPHX1 (0.49) | EPHX1HPGDRECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL17001995 | 0.78 | EPHX1 (0.49) | EPHX1HPGDRECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL22047330 | 0.76 | HPGD (0.46) | EPHX1HPGDKDM4EPKMRECQL | |
| SCHEMBL31740423 | 0.76 | CNR2 (0.44) | KDM4EPKMRECQLCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271284-A | Estrogen receptor modulators and uses thereof | 江苏威凯尔医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |