Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGAV | P06756 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838359 | 0.92 | NAMPT (0.45) | KCNK3ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL2833623 | 0.91 | ITGB3 (0.50) | KCNK3ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL2834529 | 0.89 | ITGB3 (0.51) | KCNK3ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL2841490 | 0.88 | NAMPT (0.47) | KCNK3ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL2839356 | 0.88 | NAMPT (0.47) | ITGB3ITGAVITGA2BMAPTNAMPT | |
| SCHEMBL2836989 | 0.87 | ITGB3 (0.50) | KCNK3ITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL2842605 | 0.87 | ITGB3 (0.50) | KCNK3ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL2836874 | 0.86 | TSHR (0.52) | ITGB3ITGAVMAPTL3MBTL1NAMPT | |
| SCHEMBL2833027 | 0.86 | ALDH1A1 (0.48) | KCNK3ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL2836420 | 0.85 | ITGB3 (0.51) | KCNK3ITGB3ITGAVITGA2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061448-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |