Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400754 | 0.87 | FAAH (0.35) | THRBF2PLGPRSS1PRSS2 | |
| SCHEMBL4391493 | 0.84 | OPRM1 (0.42) | THRBF2PLGPRSS1PRSS2 | |
| SCHEMBL7624346 | 0.84 | SRC (0.38) | THRBF2PLGPRSS1PRSS2 | |
| SCHEMBL1041440 | 0.80 | KMT2A (0.41) | FAAHCNR2KMT2ANPC1RAB9A | |
| SCHEMBL7619699 | 0.79 | FOXM1 (0.34) | THRBF2PLGPRSS1PRSS2 | |
| SCHEMBL13010959 | 0.76 | SRC (0.39) | FAAHCNR2KMT2AMEN1FOXM1 | |
| SCHEMBL7620857 | 0.72 | FAAH (0.37) | THRBF2PLGPRSS1PRSS2 | |
| SCHEMBL4394402 | 0.72 | OPRM1 (0.38) | THRBF2PLGPRSS1PRSS2 | |
| SCHEMBL2626924 | 0.68 | FAAH (0.55) | FAAHCNR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL8479178 | 0.68 | ESR1 (0.39) | FAAHFOXM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112274-B1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2009-12-09 | — | — | EP | disclosed |
| US-7422908-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-09-09 | — | — | US | disclosed |
| US-7416898-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-08-26 | — | — | US | disclosed |
| US-20040077018-A1 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P (US) | 2004-04-22 | — | — | US | disclosed |
| US-20030213940-A1 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P (US) | 2003-11-20 | — | — | US | disclosed |
| US-6461876-B1 | STABLE SPIROFUSED RINGS; DECOMPOSING TO GENERATE LIGHT AND CARBONYL GROUP; HIGH ENERGY; MEDICINE | TOBEN, HOWARD R. | 2002-10-08 | — | — | US | disclosed |
| EP-1112274-A4 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1112274-A1 | CHEMILUMINESCENT 1,2-DIOXETANES | Giri, Brij P. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000014092-A1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2000-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077018-A1 | Chemiluminescent 1,2-dioxetanes | CYP19A1, CYP1A1, CYP2F1 | THRB 1102/4885F2 313/4885PLG 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.