SCHEMBL43882

SCHEMBL43882

O=C(O)CCCCCCCCCCN1C(=O)C=CC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 7/20 1.00
PTGS2 P35354 7/20 1.00
MGLL Q99685 6/20 0.68
FAAH O00519 4/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
LMNA P02545 2/20 0.68
HSP90AA1 P07900 1/20 0.68
TLR9 Q9NR96 1/20 0.68
ALDH1A1 P00352 1/20 0.68
TP53 P04637 1/20 0.68
MAPT P10636 1/20 0.68
PKM P14618 1/20 0.68
HPGD P15428 1/20 0.68
XBP1 P17861 1/20 0.68
MAPK1 P28482 1/20 0.68
HTT P42858 1/20 0.68
RECQL P46063 1/20 0.68
RAB9A P51151 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
GPR35 Q9HC97 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779419 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL7785894 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL1574552 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL43969 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL8779453 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL24939859 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL6934781 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL3291535 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL6940132 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2
SCHEMBL8779402 1.00 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1762 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4635501-A2 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW Sapreme Technologies B.V. (NL) 2025-10-22 EP claimed
US-20250295800-A1 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION SAPREME TECH BV (NL) 2025-09-25 US claimed
EP-4003427-B1 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECH BV (NL) 2025-09-17 EP claimed
EP-4596052-A2 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF Sapreme Technologies B.V. (NL) 2025-08-06 EP claimed
EP-4591938-A2 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC Sapreme Technologies B.V. (NL) 2025-07-30 EP claimed
EP-4210760-B1 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC SAPREME TECH BV (NL) 2025-06-18 EP claimed
EP-4171643-B1 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF SAPREME TECH BV (NL) 2025-06-04 EP claimed
CN-120005123-A Acrylic ester block copolymer resin, photoresist, and preparation method and application thereof 中国石油化工股份有限公司 2025-05-16 CN claimed
CN-115960998-B Nucleic acid probe capable of isothermally recognizing double-stranded DNA and application thereof 刘国珍 2025-04-08 CN claimed
EP-4529953-A2 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC Sapreme Technologies B.V. (NL) 2025-04-02 EP claimed
EP-2478049-A1 A POLYMER SUPPORT University of Cape Town (ZA) 2012-07-25 EP claimed
US-20120178916-A1 Polymer Support UNIVERSITY OF CAPE TOWN (ZA) 2012-07-12 US claimed
US-20120141416-A1 MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2012-06-07 US claimed
EP-2448965-A1 MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2012-05-09 EP claimed
WO-2011083360-A1 A POLYMER SUPPORT UNIVERSITY OF CAPE TOWN (ZA) 2011-07-14 WO claimed
WO-2011000095-A1 MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2011-01-06 WO claimed
US-20100015136-A1 CAMPTOTHECIN-PEPTIDE CONJUGATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME DIATOS, S.A. (FR) 2010-01-21 US claimed
EP-1998809-A2 CAMPTOTHECIN-CELL PENETRATING PEPTIDE CONJUGATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Diatos S.A. (FR) 2008-12-10 EP claimed
US-20080075963-A1 Modified calcium carbonate-filled adhesive compositions and methods for use thereof DESIGNER MOLECULES, INC. 2008-03-27 US claimed
WO-2007113687-A2 CAMPTOTHECIN-CELL PENETRATING PEPTIDE CONJUGATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME DIATOS S.A. (FR) 2007-10-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100015136-A1 CAMPTOTHECIN-PEPTIDE CONJUGATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME VIP, SLC19A1, CXCL12 PTGS1 3361/4885PTGS2 3813/4885MGLL 3322/4885
US-20120141416-A1 MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF LNPEP, DNPEP, VIP PTGS1 3256/4885PTGS2 3524/4885MGLL 3427/4885
US-20250295800-A1 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION CYP46A1, HCCS, DHCR7 PTGS1 1677/4885PTGS2 2327/4885MGLL 2510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.