SCHEMBL4388494

SCHEMBL4388494

CCCCCCCCO[SiH](C(C)C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.39
THRB P10828 2/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
USP2 O75604 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
LPAR3 Q9UBY5 6/20 0.35
LPAR2 Q9HBW0 5/20 0.35
CA1 P00915 5/20 0.35
CA2 P00918 5/20 0.35
CA9 Q16790 5/20 0.35
LPAR1 Q92633 2/20 0.35
NAAA Q02083 1/20 0.35
CA12 O43570 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21059164 0.79 HSD17B10 (0.35)
SCHEMBL28516102 0.76 DNM1 (0.34) DNM1THRBTSHRMEN1HTT
SCHEMBL2966763 0.74 THRB (0.47) THRBTSHRMEN1HTTKMT2A
SCHEMBL2968016 0.74 THRB (0.47) THRBTSHRMEN1HTTKMT2A
SCHEMBL2542804 0.74 THRB (0.47) THRBTSHRMEN1HTTKMT2A
SCHEMBL5746153 0.74 THRB (0.47) THRBTSHRMEN1HTTKMT2A
SCHEMBL2315983 0.74 THRB (0.47) THRBTSHRMEN1HTTKMT2A
SCHEMBL2966413 0.74 THRB (0.47) THRBTSHRMEN1HTTKMT2A
SCHEMBL5197891 0.74 THRB (0.47) THRBTSHRMEN1HTTKMT2A
SCHEMBL5746879 0.74 THRB (0.47) THRBTSHRMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101668818-A Preparation of silicon and germanium phthalocyanines and related substances BASF SE 2010-03-10 CN disclosed
EP-2134792-A2 PRODUCTION OF SILICON AND GERMANIUM PHTHALOCYANINES AND RELATED SUBSTANCES BASF SE (DE) 2009-12-23 EP disclosed
WO-2008122531-A2 PRODUCTION OF SILICON AND GERMANIUM PHTHALOCYANINES AND RELATED SUBSTANCES BASF SE (DE) 2008-10-16 WO disclosed
US-5576453-A Stable, sterically-protected, bonded phase silicas prepared from bifunctional silanes ES INDUSTRIES (US) 1996-11-19 US disclosed