Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.76 |
| ▸ | ACACA | Q13085 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TACR3 | P29371 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388602 | 1.00 | ACACB (0.76) | ACACBACACAMEN1KMT2ACYP2C9 | |
| SCHEMBL4391974 | 0.93 | ACACB (0.74) | ACACBACACACYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL4391971 | 0.93 | ACACB (0.74) | ACACBACACACYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL13768020 | 0.92 | ACACB (0.76) | ACACBACACAMEN1KMT2ACYP2C9 | |
| SCHEMBL13590801 | 0.92 | ACACB (0.73) | ACACBACACAMEN1KMT2ACYP2C9 | |
| Hydrochloric Acid SCHEMBL4390263 | 0.91 | ACACB (0.72) | ACACBACACAMEN1KMT2ACYP2C9 | |
| Hydrochloric Acid SCHEMBL4390259 | 0.91 | ACACB (0.72) | ACACBACACAMEN1KMT2ACYP2C9 | |
| SCHEMBL4008494 | 0.90 | ACACB (0.80) | ACACBACACAMEN1KMT2ACYP2C9 | |
| SCHEMBL4396583 | 0.90 | ACACB (0.64) | ACACBACACACYP2C9ALDH1A1L3MBTL1 | |
| SCHEMBL4390184 | 0.89 | ACACB (0.69) | ACACBACACACYP2C9MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ACACA, ACACB, ACAT1 | ACACB 2/4885ACACA 1/4885MEN1 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.