Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390815 | 0.96 | TSHR (0.52) | TSHRPAMKLK7MAPK1SMN1; SMN2 | |
| SCHEMBL4388772 | 0.95 | TSHR (0.51) | TSHRPAMKLK7MAPK1SMN1; SMN2 | |
| SCHEMBL4389939 | 0.95 | TSHR (0.51) | TSHRPAMKLK7MAPK1SMN1; SMN2 | |
| SCHEMBL4389684 | 0.95 | TSHR (0.51) | TSHRPAMKLK7MAPK1SMN1; SMN2 | |
| SCHEMBL4389706 | 0.95 | TSHR (0.51) | TSHRPAMKLK7MAPK1SMN1; SMN2 | |
| SCHEMBL4381331 | 0.95 | TSHR (0.51) | TSHRPAMKLK7MAPK1SMN1; SMN2 | |
| SCHEMBL4383481 | 0.79 | TSHR (0.35) | TSHRHDAC11ALDH1A1AKR1B1 | |
| SCHEMBL4388761 | 0.79 | HTT (0.44) | TSHRMAPK1SMN1; SMN2HDAC3ADRA1A | |
| SCHEMBL4397149 | 0.78 | HTT (0.43) | TSHRMAPK1SMN1; SMN2HDAC3ADRA1A | |
| SCHEMBL4395384 | 0.78 | HTT (0.43) | TSHRMAPK1SMN1; SMN2HDAC3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629383-B2 | Double esters | DRUG DISCOVERY LABORATORY AS (NO) | 2009-12-08 | — | — | US | disclosed |
| US-20050203181-A1 | Double esters | DRUG DISCOVERY LABORATORY AS (NO) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203181-A1 | Double esters | ACACA, CES1, ACACB | TSHR 1933/4885PAM 2684/4885KLK7 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.