Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471223 | 0.80 | CYP3A4 (0.41) | NISCHLMNARECQL | |
| SCHEMBL11155987 | 0.80 | NISCH (0.50) | NISCHLMNARECQL | |
| SCHEMBL11301090 | 0.77 | LMNA (0.53) | NISCHLMNARECQL | |
| SCHEMBL11285481 | 0.73 | NISCH (0.54) | NISCHLMNARECQL | |
| SCHEMBL30982286 | 0.71 | LMNA (0.54) | NISCHLMNARECQL | |
| SCHEMBL10818104 | 0.71 | ALDH1A1 (0.48) | RECQL | |
| SCHEMBL11517317 | 0.70 | NISCH (0.67) | NISCHLMNARECQL | |
| SCHEMBL18824619 | 0.70 | LMNA (0.53) | NISCHLMNARECQL | |
| SCHEMBL8239326 | 0.70 | NISCH (0.57) | NISCHLMNARECQL | |
| SCHEMBL2949149 | 0.68 | NISCH (0.62) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629463-B2 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-08 | — | — | US | disclosed |
| EP-1435785-B1 | IMINOBENZOXAZINES, IMINOBENZOTHIAZINES AND IMINOQUINAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20080132524-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | CLARK DAVID ALAN | 2008-06-05 | — | — | US | disclosed |
| US-7375232-B2 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| US-7326704-B2 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| US-7148217-B2 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-12-12 | — | — | US | disclosed |
| US-20060258649-A1 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | SELBY THOMAS P | 2006-11-16 | — | — | US | disclosed |
| EP-1417204-B1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20040242645-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-12-02 | — | — | US | disclosed |
| US-20040214828-A1 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-10-28 | — | — | US | disclosed |
| EP-1417204-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. du Pont de Nemours and Company (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016304-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132524-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | AOC2, DDT, CBR3 | NISCH 53/4885LMNA 4791/4885RECQL 504/4885 |
| US-20040214828-A1 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | NR0B1, IPO5, RER1 | NISCH 19/4885LMNA 1088/4885RECQL 98/4885 |
| US-20040242645-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | AOC2, OLA1, AOC3 | NISCH 17/4885LMNA 3892/4885RECQL 821/4885 |
| US-20060258649-A1 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | NR0B1, NR1I2, NR0B2 | NISCH 166/4885LMNA 1633/4885RECQL 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.